Cost analysis of two strategies for hepatitis A vaccination of hospital health-care personnel in an intermediate endemicity area

被引：8
作者：
de Juanes, JR
González, A
Arrazola, MP
San-Martín, M
机构：
[1] Hosp 12 Octubre, Jefe Serv Med Prevent, E-28041 Madrid, Spain
[2] Aventis Pasteur MSD, Dept Med, Madrid, Spain
来源：
VACCINE | 2001年 / 19卷 / 30期
关键词：
hepatitis A; vaccination; health-care personnel;
D O I：
10.1016/S0264-410X(01)00178-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The aim of the study was to carry out a cost analysis to allow the comparison of the cost of two vaccination strategies against Hepatitis A in health-care personnel. A total of 423 health-care workers were recruited at one General Hospital of Madrid, Spain. Blood specimens were obtained for anti-HAV antibody determination. The prevalence of anti-HAV antibody was 40% (95% CI: 35-45) and it was directly correlated with age. Cost analysis determined that the critical value of prevalence for vaccination with HAV vaccine was 23%. In hospital health-care workers less than or equal to 30 years in age, vaccination with HAV vaccine (without screening) would be the less costly strategy. In those > 30 years in age, it would be less costly to screen for anti-HAV antibody first and vaccinate those who are antibody-negative. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4130 / 4134
页数：5
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