Management of obstructive sleep apnea associated with Down syndrome and other craniofacial dysmorphologies

被引:46
作者
Rosen, Dennis [1 ]
机构
[1] Harvard Univ, Childrens Hosp Boston, Sch Med, Ctr Pediat Sleep Disorders,Div Resp Dis, Boston, MA 02115 USA
关键词
cine MRI of upper airway in Down syndrome; complications of adenotonsillectomy in children with Down syndrome; continuous positive airway pressure in Down syndrome; maxillary hypoplasia in Down syndrome; outcome of adenotonsillectomy in children with Down syndrome; spontaneous resolution of obstructive sleep apnea in infants with Down syndrome; UPPER AIRWAY-OBSTRUCTION; PULMONARY-HYPERTENSION; PREVIOUS TONSILLECTOMY; SURGICAL-MANAGEMENT; RISK-FACTORS; CHILDREN; ADENOTONSILLECTOMY; PREVALENCE; COMPLICATIONS; ADENOIDECTOMY;
D O I
10.1097/MCP.0b013e32834ba9c0
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Purpose of review Obstructive sleep apnea (OSA) is very common in children with Down syndrome and other craniofacial abnormalities and causes significant deleterious physical, developmental, and behavioral outcomes. OSA in these individuals is generally more difficult to treat than in other children, because of increased postoperative complications and lower success rates for adenotonsillectomy, the mainstay of treatment for otherwise healthy children with OSA. Recent findings There is a growing number of treatment options for these children, which can provide an alternative to continuous positive airway pressure or tracheostomy. Through the use of dynamic cine MRI studies, the level of obstruction can be identified and treatment made more focused. Summary Screening for OSA in this population should be increased, and utilization made of the recent advances in imaging and surgical technique to treat it.
引用
收藏
页码:431 / 436
页数:6
相关论文
共 85 条
  • [1] Tracheostomy in Children: A Population-Based Experience Over 17 Years
    Al-Samri, Mohammed
    Mitchell, Ian
    Drummond, Derek S.
    Bjornson, Candice
    [J]. PEDIATRIC PULMONOLOGY, 2010, 45 (05) : 487 - 493
  • [2] Adenotonsillectomy for Sleep-Disordered Breathing in Children With Syndromic Craniosynostosis
    Amonoo-Kuofi, Kwamena
    Phillips, Seamus P.
    Randhawa, Premjit S.
    Lane, Roderick
    Wyatt, Michelle E.
    Leighton, Susanna E. J.
    [J]. JOURNAL OF CRANIOFACIAL SURGERY, 2009, 20 (06) : 1978 - 1980
  • [3] Cognitive status in Down syndrome individuals with sleep disordered breathing deficits (SDB)
    Andreou, G
    Galanopoulou, C
    Gourgoulianis, K
    Karapetsas, A
    Molyvdas, P
    [J]. BRAIN AND COGNITION, 2002, 50 (01) : 145 - 149
  • [4] Pulmonary hypertension resulting from upper airways obstruction in Down's syndrome
    Ayeni, TI
    Roper, HP
    [J]. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 1998, 91 (06) : 321 - 322
  • [5] Obstructive sleep apnea in children with syndromic craniosynostosis: long-term respiratory outcome of midface advancement
    Bannink, N.
    Nout, E.
    Wolvius, E. B.
    Hoeve, H. L. J.
    Joosten, K. F. M.
    Mathijssen, I. M. J.
    [J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2010, 39 (02) : 115 - 121
  • [6] OBSTRUCTIVE SLEEP-APNEA IN INFANTS AND CHILDREN
    BROUILLETTE, RT
    FERNBACH, SK
    HUNT, CE
    [J]. JOURNAL OF PEDIATRICS, 1982, 100 (01) : 31 - 40
  • [7] SLEEP-DISORDERED BREATHING AND BEHAVIOR IN 3 RISK GROUPS - PRELIMINARY FINDINGS FROM PARENTAL REPORTS
    CARSKADON, MA
    PUESCHEL, SM
    MILLMAN, RP
    [J]. CHILDS NERVOUS SYSTEM, 1993, 9 (08) : 452 - 457
  • [8] Sleep-disordered breathing, behavior, and cognition in children before and after adenotonsillectomy
    Chervin, RD
    Ruzicka, DL
    Giordani, BJ
    Weatherly, RA
    Dillon, JE
    Hodges, EK
    Marcus, CL
    Guire, KE
    [J]. PEDIATRICS, 2006, 117 (04) : E769 - E778
  • [9] SLEEP-INDUCED VENTILATORY DYSFUNCTION IN DOWNS-SYNDROME
    CLARK, RW
    SCHMIDT, HS
    SCHULLER, DE
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1980, 140 (01) : 45 - 50
  • [10] Sleep Outcomes in Children With Hemifacial Microsomia and Controls: A Follow-up Study
    Cloonan, Yona K.
    Kifle, Yemiserach
    Davis, Scott
    Speltz, Matthew L.
    Werler, Martha M.
    Starr, Jacqueline R.
    [J]. PEDIATRICS, 2009, 124 (02) : E313 - E321