Adenocarcinoma of the small bowel

被引:26
作者
Hutchins, RR [1 ]
Hani, AB [1 ]
Kojodjojo, P [1 ]
Ho, R [1 ]
Snooks, SJ [1 ]
机构
[1] King George Hosp, Goodmayes, Essex, England
关键词
adenocarcinoma; neoplasm; oncogene; small bowel; tumour suppressor gene;
D O I
10.1046/j.1440-1622.2001.02149.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Cancer of the small bowel is a rare entity but its incidence is rising. Historically, outcome is poor despite apparent curative resection. At present surgery remains the only treatment modality of proven benefit in the management of this disease. Recent data would suggest 5-year survival rates in the order of 40-50% at all sites of small bowel cancer. To improve upon this, earlier diagnosis with a high index of suspicion and multicentre adjuvant therapy trials are required.
引用
收藏
页码:428 / 437
页数:10
相关论文
共 109 条
[1]   Molecular pathogenesis of sporadic duodenal cancer [J].
Achille, A ;
Baron, A ;
Zamboni, G ;
Orlandini, S ;
Bogina, G ;
Bassi, C ;
Iacono, C ;
Scarpa, A .
BRITISH JOURNAL OF CANCER, 1998, 77 (05) :760-765
[2]  
Adekunle O O, 1973, Int Surg, V58, P708
[3]  
ADLER SN, 1982, AM J GASTROENTEROL, V77, P326
[4]   Familial adenomatous polyposis - Efficacy of endoscopic and surgical treatment for advanced duodenal adenomas [J].
Alarcon, FJ ;
Burke, CA ;
Church, JM ;
van Stolk, RU .
DISEASES OF THE COLON & RECTUM, 1999, 42 (12) :1533-1536
[5]   PRIMARY-CARCINOMA OF THE DUODENUM [J].
ALWMARK, A ;
ANDERSSON, A ;
LASSON, A .
ANNALS OF SURGERY, 1980, 191 (01) :13-18
[6]   Primary cancer of the small intestine and mutational analysis of the K-ras and p53 genes [J].
Amano, M ;
Imai, Y ;
Hashimoto, T ;
Saito, Y ;
Miyaoka, M ;
Kawaguchi, M ;
Saito, T .
JOURNAL OF GASTROENTEROLOGY, 1998, 33 (03) :397-401
[7]  
Andersen SN, 1999, SCAND J GASTROENTERO, V34, P611
[8]  
Arai M, 1997, INT J CANCER, V70, P390, DOI 10.1002/(SICI)1097-0215(19970207)70:4<390::AID-IJC3>3.0.CO
[9]  
2-R
[10]   Primary adenocarcinoma of the duodenum in the elderly: Clinicopathological and immunohistochemical study of 17 cases [J].
Arai, T ;
Murata, T ;
Sawabe, M ;
Takubo, K ;
Esaki, Y .
PATHOLOGY INTERNATIONAL, 1999, 49 (01) :23-29