Adsorption detection for polylysine biomolecules based on high-Q silica capillary whispering gallery mode microresonator

被引：3
作者：
Wu, Jixuan [1 ]
Liu, Bo [1 ]
Zhang, Hao [1 ]
Song, Binbin [2 ]
机构：
[1] Nankai Univ, Key Lab Opt Informat Sci & Technol, Minist Educ,Inst Modern Opt, Tianjin Key Lab Optoelect Sensor & Sensing Networ, Tianjin 300350, Peoples R China
[2] Tianjin Univ Technol, Key Lab Comp Vis & Syst, Minist Educ, Sch Comp Sci & Engn, Tianjin 300384, Peoples R China
来源：
MEASUREMENT SCIENCE AND TECHNOLOGY | 2017年 / 28卷 / 11期
基金：
中国国家自然科学基金;
关键词：
polylysine adsorption process; whispering gallery modes; microresonator; biological sensing; LABEL-FREE DETECTION; RING-RESONATOR; CARBAMATE PESTICIDES; SENSOR;
D O I：
10.1088/1361-6501/aa86a0
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A silica-capillary-based whispering gallery mode (WGM) microresonator has been proposed and experimentally demonstrated for the real-time monitoring of the polylysine adsorption process. The spectral characteristics of the WGM resonance dips with high quality factor and good wavelength selectivity have been investigated to evaluate the dynamic process for the binding of polylysine with a capillary surface. The WGM transmission spectrum shows a regular shift with increments of observation time, which could be exploited for the analysis of the polylysine adsorption process. The proposed WGM microresonator system possesses desirable qualities such as high sensitivity, fast response, label-free method, high detection resolution and compactness, which could find promising applications in histology and related bioengineering areas.
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页数：6
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