Genomic analysis of 6,000-year-old cultivated grain illuminates the domestication history of barley

被引：100

作者：

Mascher, Martin ^{[1
,2
]}

Schuenemann, Verena J. ^{[3
,4
]}

Davidovich, Uri ^{[5
]}

Marom, Nimrod ^{[6
]}

Himmelbach, Axel ^{[1
]}

Hubner, Sariel ^{[7
,8
]}

Korol, Abraham ^{[9
,10
]}

David, Michal ^{[11
]}

Reiter, Ella ^{[3
]}

Riehl, Simone ^{[3
,4
]}

Schreiber, Mona ^{[1
]}

Vohr, Samuel H. ^{[12
]}

Green, Richard E. ^{[12
]}

Dawson, Ian K. ^{[13
]}

Russell, Joanne ^{[13
]}

Kilian, Benjamin ^{[1
,18
]}

Muehlbauer, Gary J. ^{[14
,15
]}

Waugh, Robbie ^{[13
,16
]}

Fahima, Tzion ^{[9
,10
]}

Krause, Johannes ^{[3
,4
,17
]}

Weiss, Ehud ^{[11
]}

Stein, Nils ^{[1
]}

机构：

[1] Leibniz Inst Plant Genet & Crop Plant Res IPK Gat, Seeland, Germany

[2] German Ctr Integrat Biodivers Res iDiv, Leipzig, Germany

[3] Univ Tubingen, Inst Archaeol Sci, Tubingen, Germany

[4] Univ Tubingen, Senckenberg Ctr Human Evolut & Paleoenvironm, Tubingen, Germany

[5] Hebrew Univ Jerusalem, Inst Archaeol, Jerusalem, Israel

[6] Univ Haifa, Zinman Inst Archaeol, Lab Archaeozool, Haifa, Israel

[7] Univ British Columbia, Dept Bot, Vancouver, BC, Canada

[8] Tel Hai Coll, Dept Biotechnol, Upper Galilee, Israel

[9] Univ Haifa, Inst Evolut, Haifa, Israel

[10] Univ Haifa, Dept Evolutionary & Environm Biol, Haifa, Israel

[11] Bar Ilan Univ, Martin Szusz Dept Land Israel Studies & Archaeol, Ramat Gan, Israel

[12] Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA

[13] James Hutton Inst, Cell & Mol Sci, Dundee, Scotland

[14] Univ Minnesota, Dept Plant Biol, St Paul, MN USA

[15] Univ Minnesota, Dept Agron & Plant Genet, St Paul, MN USA

[16] Univ Dundee, Div Plant Sci, Dundee, Scotland

[17] Max Planck Inst Sci Human Hist, Jena, Germany

[18] Bayer CropSci, BCS Breeding & Trait Dev, Ghent, Belgium

来源：

NATURE GENETICS | 2016年 / 48卷 / 09期

基金：

以色列科学基金会;

关键词：

ANCIENT DNA; GENETIC-EVIDENCE; HORDEUM-VULGARE; EVOLUTION; ADMIXTURE; REVEALS; ORIGIN; LANDRACES; SEQUENCES; FRAMEWORK;

D O I：

10.1038/ng.3611

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The cereal grass barley was domesticated about 10,000 years before the present in the Fertile Crescent and became a founder crop of Neolithic agriculture(1). Here we report the genome sequences of five 6,000-year-old barley grains excavated at a cave in the Judean Desert close to the Dead Sea. Comparison to whole-exome sequence data from a diversity panel of present-day barley accessions showed the close affinity of ancient samples to extant landraces from the Southern Levant and Egypt, consistent with a proposed origin of domesticated barley in the Upper Jordan Valley. Our findings suggest that barley landraces grown in present-day Israel have not experienced major lineage turnover over the past six millennia, although there is evidence for gene flow between cultivated and sympatric wild populations. We demonstrate the usefulness of ancient genomes from desiccated archaeobotanical remains in informing research into the origin, early domestication and subsequent migration of crop species.

引用

页码：1089 / +

页数：7

共 59 条

[1] Estimating the outcrossing rate of barley landraces and wild barley populations collected from ecologically different regions of Jordan [J].