Amyloid precursor protein mRNAs in Alzheimer's disease

被引：11
|
作者：
Harrison, PJ
WightonBenn, WH
Heffernan, JM
Sanders, MW
Pearson, RCA
机构：
[1] UNIV OXFORD, DEPT PSYCHIAT, OXFORD OX1 2JD, ENGLAND
[2] UNIV OXFORD, DEPT CLIN NEUROL NEUROPATHOL, OXFORD OX1 2JD, ENGLAND
[3] UNIV SHEFFIELD, DEPT BIOMED SCI, SHEFFIELD S10 2TN, S YORKSHIRE, ENGLAND
[4] UNIV SHEFFIELD, DEPT PSYCHIAT, SHEFFIELD S10 2TN, S YORKSHIRE, ENGLAND
来源：
NEURODEGENERATION | 1996年 / 5卷 / 04期
基金：
英国惠康基金;
关键词：
beta-amyloid; dementia; gene expression; human brain; in situ hybridization; messenger RNA;
D O I：
10.1006/neur.1996.0055
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Hybridization studies of mRNA link genetic with neurochemical and neuropathological approaches to Alzheimer's disease (AD). Here we review the distribution and abundance of amyloid precursor protein mRNAs in normal and AD-afflicted brains. The expression of apolipoprotein E and presenilin mRNAs are also discussed. (C) 1996 Academic Press Limited
引用
收藏
页码：409 / 415
页数：7
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