Regioselective synthesis of silylated pyrazolines and indazolines by reaction of pyrazolium and indazolium salts with silyllithium reagents

被引：13

作者：

González-Nogal, AM ^{[1
]}

Calle, M ^{[1
]}

Calvo, LA ^{[1
]}

Cuadrado, P ^{[1
]}

González-Ortega, A ^{[1
]}

机构：

[1] Univ Valladolid, Dept Quim Organ, Valladolid 47011, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 2005卷 / 21期

关键词：

nitrogen heterocycles; regioselectivity; silylazolines;

D O I：

10.1002/ejoc.200500438

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrazolium salts react with dimethylphenylsilyl- and tert-butyldiphenylsilyllithium to give, in general, only one of the two possible 5-silyl-3-pyrazolines. On the other hand, indazolium and isoindazolium salts lead to 3-silylindazolines and occasionally to compounds resulting from the opening or expansion of the heterocyclic ring. All of these compounds are interesting synthons in organic chemistry.

引用

页码：4663 / 4669

页数：7

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