Magnetotransport properties have been investigated in a La0.7Sr0.3MnO3/Si heterostructure, which exhibits good rectifying behaviour and voltage-modulated negative and positive magnetoresistance effects. The application of magnetic fields induces an increase in the current at a low bias voltage and a decrease at a high bias. This is caused by the effect of the voltage on the ferromagnetic state in the La0.7Sr0.3MnO3 film at the interface by the field-direction-dependent lattice distortion at a high bias voltage.