Optical coherence tomography system requirements for clinical diagnostic middle ear imaging

被引：17
作者：
MacDougall, Dan [1 ,2 ]
Rainsbury, James [3 ]
Brown, Jeremy [1 ,2 ]
Bance, Manohar [1 ,2 ,3 ]
Adamson, Robert [1 ,2 ]
机构：
[1] Dalhousie Univ, Fac Engn, Sch Biomed Engn, Halifax, NS B3H 4R2, Canada
[2] Dalhousie Univ, Fac Med, Sch Biomed Engn, Halifax, NS B3H 4R2, Canada
[3] Dalhousie Univ, Fac Med, Dept Surg, Halifax, NS B3H 2Y9, Canada
来源：
JOURNAL OF BIOMEDICAL OPTICS | 2015年 / 20卷 / 05期
关键词：
optical coherence tomography; otology; middle ear; TYMPANIC MEMBRANE; SPECKLE REDUCTION; OCT; TISSUES; RANGE;
D O I：
10.1117/1.JBO.20.5.056008
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Noninvasive middle ear imaging using optical coherence tomography (OCT) presents some unique challenges for real-time, clinical use in humans. We present results from a two-dimensional/three-dimensional OCT system built to assess the imaging requirements of clinical middle ear imaging, and the technical challenges associated with them. These include the need to work at a low numerical aperture, the deleterious effects of transtympanic imaging on image quality at the ossicles, sensitivity requirements for clinical fidelity of images at real-time rates, and the high dynamic-range requirements of the ear. We validated the system by imaging cadaveric specimens with simulated disorders to show the clinical applicability of the images. We also provide additional insight into the likely role of OCT in clinical otology. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数：8
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