Emerging Treatments for Choroidal Metastases

被引：33

作者：

Chen, Connie J. ^{[1
]}

McCoy, Allison N. ^{[1
]}

Brahmer, Julie ^{[2
]}

Handa, James T. ^{[1
]}

机构：

[1] Wilmer Eye Inst, Baltimore, MD 21287 USA

[2] Johns Hopkins Sch Med, Dept Oncol, Baltimore, MD 21287 USA

来源：

SURVEY OF OPHTHALMOLOGY | 2011年 / 56卷 / 06期

关键词：

choroidal metastases; ocular metastases; targeted therapy; CELL LUNG-CANCER; EXTERNAL-BEAM RADIOTHERAPY; GAMMA-KNIFE RADIOSURGERY; GROWTH-FACTOR RECEPTOR; PHOTODYNAMIC THERAPY; BREAST-CANCER; PLAQUE RADIOTHERAPY; RADIATION RETINOPATHY; UVEAL MELANOMAS; DRUG-THERAPY;

D O I：

10.1016/j.survophthal.2011.05.001

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

It has been over a century since Pens described the first. case of choroidal metastasis. For the next six decades only 230 cases were described in the literature. Today, however, ocular metastasis is recognized as the most common intraocular malignancy. Thanks to recent advances in treatment options for metastatic disease, patients are living longer, and choroidal metastases will become an increasingly important issue for oncologists and ophthalmologists alike. We summarize the current knowledge of choroidal metastases and examine their emerging systemic and local therapies. Targeted therapies for metastatic lung, breast, and colon cancer-the most common causes of choroidal metastases-are reviewed in detail with the goal of identifying the most effective treatment strategies. (Surv Ophthalmol 56:511-521, 2011. (C) 2011 Elsevier Inc. All rights reserved.)

引用

页码：511 / 521

页数：11

共 73 条

[1]

Altekruse SF., 1975, SEER cancer statistics review

[2] Treatment options in the management of choroidal metastases [J].

Amer, R ;

Pe'er, J ;

Chowers, I ;

Anteby, I .

OPHTHALMOLOGICA, 2004, 218 (06) :372-377

[3] Intravitreal bevacizumab (Avastin) for choroidal metastasis secondary to breast carcinoma:: short-term follow-up [J].

Amselem, L. ;

Cervera, E. ;

Diaz-Llopis, M. ;

Montero, J. ;

Garcia-Pous, M. ;

Udaondo, P. ;

Garcia-Delpech, S. ;

Salom, D. .

EYE, 2007, 21 (04) :566-567

[4]

Battikh M H, 2004, Rev Pneumol Clin, V60, P353

[5] Stereotactic radiation therapy for malignant choroidal tumors -: Preliminary, short-term results [J].

Bellmann, C ;

Fuss, M ;

Holz, FG ;

Debus, J ;

Rohrschneider, K ;

Völcker, HE ;

Wannenmacher, M .

OPHTHALMOLOGY, 2000, 107 (02) :358-365

[6] Restoration of vision following combination chemotherapy of nasopharyngeal carcinoma choroidal metastases [J].

Biswal, BM .

MEDICAL AND PEDIATRIC ONCOLOGY, 2001, 37 (05) :484-484

[7]

BLOCH RS, 1971, ARCH OPHTHALMOL-CHIC, V85, P673

[8]

BRINKLEY JR, 1980, CANCER, V45, P1538, DOI 10.1002/1097-0142(19800401)45:7<1538::AID-CNCR2820450704>3.0.CO

[9]

2-G

[10] Breast Cancer [J].

Carlson, Robert W. ;

Allred, D. Craig ;

Anderson, Benjamin O. ;

Burstein, Harold J. ;

Carter, W. Bradford ;

Edge, Stephen B. ;

Erban, John K. ;

Farrar, William B. ;

Goldstein, Lori J. ;

Gradishar, William J. ;

Hayes, Daniel F. ;

Hudis, Clifford A. ;

Jahanzeb, Mohammad ;

Kiel, Krystyna ;

Ljung, Britt-Marie ;

Marcom, P. Kelly ;

Mayer, Ingrid A. ;

McCormick, Beryl ;

Nabell, Lisle M. ;

Pierce, Lori J. ;

Reed, Elizabeth C. ;

Smith, Mary Lou ;

Somlo, George ;

Theriault, Richard L. ;

Topham, Neal S. ;

Ward, John H. ;

Winer, Eric P. ;

Wolff, Antonio C. .

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2009, 7 (02) :122-+

← 1 2 3 4 5 6 7 8 →