Hyperprogression under treatment with immune-checkpoint inhibitors in patients with gastrointestinal cancer: A natural process of advanced tumor progression?

被引：0
作者：
Wang, Mo-Xuan [1 ]
Gao, Shu-Yue [1 ]
Yang, Fan [1 ]
Fan, Run-Jia [1 ]
Yang, Qin-Na [1 ]
Zhang, Tian-Lan [1 ]
Qian, Nian-Song [2 ,4 ]
Dai, Guang-Hai [3 ]
机构：
[1] Chinese PLA Med Sch, Dept Oncol, Beijing 100853, Peoples R China
[2] Chinese Peoples Liberat Army Gen Hosp, Dept Oncol, Sr Dept Resp & Crit Care Med, Med Ctr 8, Beijing 100853, Peoples R China
[3] Chinese Peoples Liberat Army Gen Hosp, Dept Oncol, Med Ctr 5, Beijing 100853, Peoples R China
[4] Chinese Peoples Liberat Army Gen Hosp, Dept Oncol, Sr Dept Resp & Crit Care Med, Med Ctr 8, 17 Heishanhu Rd, Beijing 100853, Peoples R China
来源：
WORLD JOURNAL OF CLINICAL ONCOLOGY | 2022年 / 13卷 / 09期
关键词：
Hyperprogressive; Immunotherapy; Natural process; Gastric cancer; Colorectal cancer; REGULATORY T-CELLS; STABILIZES MDM2; TGF-BETA; IMMUNOTHERAPY; BLOCKADE; INFLAMMATION; PROGNOSIS; DISEASE; FLARE;
D O I：
10.5306/wjco.v13.i9.729
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Immunotherapy has shown great promise in treating various types of malignant tumors. However, some patients with gastrointestinal cancer have been known to experience rapid disease progression after treatment, a situation referred to as hyperprogressive disease (HPD). This minireview focuses on the definitions and potential mechanisms of HPD, natural disease progression in gastrointestinal malignancies, and tumor immunological microenvironment.
引用
收藏
页码：729 / 737
页数：9
相关论文
共 50 条
  • [1] Redefine Hyperprogressive Disease During Treatment With Immune-Checkpoint Inhibitors in Patients With Gastrointestinal Cancer
    Wang, Zhenghang
    Liu, Chang
    Bai, Yuezong
    Zhao, Xiaochen
    Cui, Longgang
    Peng, Zhi
    Zhang, Xiaotian
    Wang, Xicheng
    Zhao, Zhengyi
    Li, Jian
    Shen, Lin
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [2] Role of immune checkpoint inhibitors in gastrointestinal cancer treatment
    Riedl, Jakob Michael
    Stotz, Michael
    Gerger, Armin
    MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, 2019, 12 (01) : 71 - 76
  • [3] Role of immune checkpoint inhibitors in gastrointestinal cancer treatment
    Jakob Michael Riedl
    Michael Stotz
    Armin Gerger
    memo - Magazine of European Medical Oncology, 2019, 12 : 71 - 76
  • [4] Palliative radiotherapy in advanced cancer patients treated with immune-checkpoint inhibitors: The PRACTICE study
    Bersanelli, Melissa
    Lattanzi, Elisabetta
    D'Abbiero, Nunziata
    Buti, Sebastiano
    Leonetti, Alessandro
    Cane, Maria Giulia
    Trapani, Salvatore
    Gravina, Giovanni Luca
    Porzio, Giampiero
    Cannita, Katia
    Di Marino, Pietro
    Grassadonia, Antonino
    Tinari, Nicola
    De Tursi, Michele
    Giaiacopi, Elisa
    Michiara, Maria
    Bordi, Paola
    Perrone, Fabiana
    Caravatta, Luciana
    Trignani, Marianna
    Genovesi, Domenico
    Natoli, Clara
    Ficorella, Corrado
    Tiseo, Marcello
    Cortellini, Alessio
    BIOMEDICAL REPORTS, 2020, 12 (02) : 59 - 67
  • [5] Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors
    de Moel, Emma C.
    Rozeman, Elisa A.
    Kapiteijn, Ellen H.
    Verdegaal, Els M. E.
    Grummels, Annette
    Bakker, Jaap A.
    Huizinga, Tom W. J.
    Haanen, John B.
    Toes, Rene E. M.
    van der Woude, Diane
    CANCER IMMUNOLOGY RESEARCH, 2019, 7 (01) : 6 - 11
  • [6] Immune-checkpoint inhibitors for the treatment of metastatic melanoma: a model of cancer immunotherapy
    Queirolo, Paola
    Boutros, Andrea
    Tanda, Enrica
    Spagnolo, Francesco
    Quaglino, Pietro
    SEMINARS IN CANCER BIOLOGY, 2019, 59 : 290 - 297
  • [7] Targeting myeloid villains in the treatment with immune checkpoint inhibitors in gastrointestinal cancer
    Kudo-Saito, Chie
    Boku, Narikazu
    Hirano, Hidekazu
    Shoji, Hirokazu
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [8] Cancer-related fatigue among patients with advanced cancer receiving immune-checkpoint inhibitors: a prospective study
    Yennurajalingam, Sriram
    Thomas, Lisa
    Stanton, Penny A.
    Lu, Zhanni
    de Moraes, Aline Rozman
    Bruera, Eduardo
    SUPPORTIVE CARE IN CANCER, 2024, 32 (07)
  • [9] Impact of immune checkpoint inhibitors on atherosclerosis progression in patients with lung cancer
    Drobni, Zsofia Dora
    Gongora, Carlos
    Taron, Jana
    Suero-Abreu, Giselle A.
    Karady, Julia
    Gilman, Hannah K.
    Supraja, Sama
    Nikolaidou, Sofia
    Leeper, Nicolas
    Merkely, Bela
    Maurovich-Horvat, Pal
    Foldyna, Borek
    Neilan, Tomas G.
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (07)
  • [10] Immunotherapy with Immune Checkpoint Inhibitors for Advanced Colorectal Cancer: A Promising Individualized Treatment Strategy
    Yang, Ying
    Meng, Wen-Jian
    Wang, Zi-Qiang
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2023, 28 (04):
12345