Lupus nephritis management guidelines compared

被引：83

作者：

Wilhelmus, Suzanne ^{[1
]}

Bajema, Ingeborg M. ^{[1
]}

Bertsias, George K. ^{[2
,3
]}

Boumpas, Dimitrios T. ^{[3
,4
]}

Gordon, Caroline ^{[5
]}

Lightstone, Liz ^{[6
]}

Tesar, Vladimir ^{[7
]}

Jayne, David R. ^{[8
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands

[2] Univ Crete, Sch Med, Rheumatol Clin Immunol & Allergy, Iraklion, Greece

[3] FORTH, IMBB, Infect & Immun Div, Iraklion, Greece

[4] Acad Athens, Biomed Res Fdn, Athens, Greece

[5] Univ Birmingham, Coll Med & Dent Sci, Sch Immun & Infect, Rheumatol Res Grp,Med Sch, Birmingham, W Midlands, England

[6] Imperial Coll London, Dept Med, Sect Renal Med & Vasc Inflammat, London, England

[7] Charles Univ Prague, Sch Med 1, Dept Nephrol, Prague, Czech Republic

[8] Addenbrookes Hosp, Lupus & Vasculitis Unit, Cambridge, England

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 2016年 / 31卷 / 06期

关键词：

guideline; lupus nephritis; management; systemic lupus erythematosus; treatment; MYCOPHENOLATE-MOFETIL; MEMBRANOUS NEPHROPATHY; MAINTENANCE THERAPY; INDUCTION THERAPY; EUROPEAN LEAGUE; RENAL BIOPSY; ERYTHEMATOSUS; AZATHIOPRINE; RITUXIMAB; CYCLOPHOSPHAMIDE;

D O I：

10.1093/ndt/gfv102

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis. These guidelines are European, American and internationally based, with one separate guideline for children. They offer information on different aspects of the management of lupus nephritis including induction and maintenance treatment of the different histological classes, adjunctive treatment, monitoring of the patient, definitions of response and relapse, indications for (repeat) renal biopsy, and additional challenges such as the presence of vascular complications, the pregnant SLE patient, treatment in children and adolescents and considerations about end-stage renal disease and transplantation. In this review, we summarize the guidelines, determine the common ground between them, highlight the differences and discuss recent literature.

引用

页码：904 / 913

页数：10