A facile and regioselective one-pot synthesis of novel pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylate hybrids via intramolecular Wittig reaction

被引：0

作者：

Largani, Tahere Hosseyni ^{[1
]}

Imanzadeh, Gholamhasan ^{[1
]}

Pesyan, Nader Noroozi ^{[2
]}

Sahin, Ertan ^{[3
]}

Shamkhali, Amir Nasser ^{[1
]}

Notash, Behrouz ^{[4
]}

机构：

[1] Univ Mohaghegh Ardabili, Dept Chem, Fac Sci, Ardebil 5619911367, Iran

[2] Urmia Univ, Dept Chem, Fac Sci, Orumiyeh 57159, Iran

[3] Ataturk Univ, Dept Chem, Fac Sci, TR-25240 Erzurum, Turkey

[4] ShahidBeheshti Univ, Dept Chem, Tehran 1983963113, Iran

来源：

MOLECULAR DIVERSITY | 2018年 / 22卷 / 01期

关键词：

Regioselective; One-pot synthesis; Pyrrolo[3,4-b]quinoline; Wittig reaction; Pyrazole; Hybrid molecules; SOLVENT-FREE CONDITIONS; PYRAZOLE DERIVATIVES; PHOSPHORUS YLIDES; EFFICIENT; DENSITY; DESIGN; DRUG;

D O I：

10.1007/s11030-017-9784-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The regioselective syntheses of novel pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylates (6a-l) from pyrrolo([3,4-b]quinolin-2(3H)-yl)benzamides through an intramolecular Wittig reaction are described. This protocol takes advantages of mild conditions, simple workup and high yield which make this method attractive for the synthesis of these hybrid of pyrazolo[1,5:1,2]pyrrolo[3,4-b]quinolines.

引用

页码：37 / 46

页数：10

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