The X chromosome in population genetics

被引：178

作者：

Schaffner, SF ^{[1
]}

机构：

[1] Whitehead MIT, Ctr Genome Res, Cambridge, MA 02139 USA

来源：

NATURE REVIEWS GENETICS | 2004年 / 5卷 / 01期

关键词：

D O I：

10.1038/nrg1247

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic variation records a large amount of information about the history of a species and about the processes that create and shape that variation. Owing to the way in which it is inherited, the X chromosome is a rich resource of easily accessible genetic data, and therefore provides a unique tool for population-genetic studies. The potential of the human X chromosome, which rivals that of the more traditional mtDNA and Y chromosome, has only just begun to be tapped.

引用

页码：43 / 51

页数：9

共 62 条

[1] DNA variation in a 5-Mb region of the X chromosome and estimates of sex-specific/type-specific mutation rates [J].

Anagnostopoulos, T ;

Green, PM ;

Rowley, G ;

Lewis, CM ;

Giannelli, F .

AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 64 (02) :508-517

[2] SEQUENCE AND ORGANIZATION OF THE HUMAN MITOCHONDRIAL GENOME [J].

ANDERSON, S ;

BANKIER, AT ;

BARRELL, BG ;

DEBRUIJN, MHL ;

COULSON, AR ;

DROUIN, J ;

EPERON, IC ;

NIERLICH, DP ;

ROE, BA ;

SANGER, F ;

SCHREIER, PH ;

SMITH, AJH ;

STADEN, R ;

YOUNG, IG .

NATURE, 1981, 290 (5806) :457-465

[3] Reduced X-linked nucleotide polymorphism in Drosophila simulans [J].

Begun, DJ ;

Whitley, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (11) :5960-5965

[4] Unexpectedly similar rates of nucleotide substitution found in male and female hominids [J].

Bohossian, HB ;

Skaletsky, H ;

Page, DC .

NATURE, 2000, 406 (6796) :622-625

[5] MITOCHONDRIAL-DNA AND HUMAN-EVOLUTION [J].

CANN, RL ;

STONEKING, M ;

WILSON, AC .

NATURE, 1987, 325 (6099) :31-36

[6]

CHANG BH, 1994, P NATL ACAD SCI USA, V18, P827

[7]

CHANG BHJ, 1995, J MOL EVOL, V40, P70, DOI 10.1007/BF00166597

[8]

CHARLESWORTH B, 1993, GENETICS, V134, P1289

[9] Genomewide comparison of DNA sequences between humans and chimpanzees [J].

Ebersberger, I ;

Metzler, D ;

Schwarz, C ;

Pääbo, S .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (06) :1490-1497

[10] The structure of haplotype blocks in the human genome [J].

Gabriel, SB ;

Schaffner, SF ;

Nguyen, H ;

Moore, JM ;

Roy, J ;

Blumenstiel, B ;

Higgins, J ;

DeFelice, M ;

Lochner, A ;

Faggart, M ;

Liu-Cordero, SN ;

Rotimi, C ;

Adeyemo, A ;

Cooper, R ;

Ward, R ;

Lander, ES ;

Daly, MJ ;

Altshuler, D .

SCIENCE, 2002, 296 (5576) :2225-2229

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