Multifocal Cutaneous Orf Virus Infection in Goats in the Amazon Region, Brazil

被引:21
作者
de Oliveira, Cairo H. S. [2 ]
Assis, Felipe L.
Neto, Jose Diomedes B. [3 ]
Oliveira, Carlos M. C. [3 ]
Lopes, Cinthia Tavora de A. [3 ]
Bomjardim, Henrique dos A. [3 ]
Vinhote, Wagner M. S. [3 ]
Silva, Andre G. M. [3 ]
Abrahao, Jonatas S.
Kroon, Erna G. [1 ]
机构
[1] Univ Fed Minas Gerais, Virus Lab, Dept Microbiol, Inst Ciencias Biol, BR-31270901 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Escola Vet, BR-31270901 Belo Horizonte, MG, Brazil
[3] Fed Univ Para, Cent Diagnost Vet Fac Vet, BR-66059 Belem, PA, Brazil
关键词
Animals; Diagnostics; Domestic; Field studies; Microbiology; Orf virus; Zoonosis;
D O I
10.1089/vbz.2011.0725
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Orf virus is the etiological agent of contagious ecthyma, a severe exanthematic disease that affects small ruminants. Orf virus is zoonosis that is associated with occupational contact with infected animals in human disease. Clinically, contagious ecthyma is characterized by the appearance of vesicles, pustules, ulcers, and papillomatous proliferative lesions on the skin of the lips and nostrils. Here we describe a case of lethal cutaneous multifocal Orf virus infection in goats in the Amazon region of Brazil. Exanthematic lesions were collected and epidemiological and clinical data were obtained. Orf virus was detected using PCR amplification of the whole B2L, VIR, and VEGF open reading frame. Phylogenetic analysis revealed that this virus clustered together with the Orf virus samples isolated during classical contagious ecthyma. The present work is the first to report a severe proliferative Orf virus case in South America.
引用
收藏
页码:336 / 340
页数:5
相关论文
共 11 条
[1]   Detection and phylogenetic analysis of Orf virus from sheep in Brazil: a case report [J].
Abrahao, Jonatas S. ;
Campos, Rafael K. ;
Trindade, Giliane S. ;
Guedes, Maria I. M. ;
Lobato, Zelia I. P. ;
Mazur, Carlos ;
Ferreira, Paulo C. P. ;
Bonjardim, Claudio A. ;
Kroon, Erna G. .
VIROLOGY JOURNAL, 2009, 6
[2]   Rapid Detection of Orthopoxvirus by Semi-Nested PCR Directly From Clinical Specimens: A Useful Alternative for Routine Laboratories [J].
Abrahao, Jonatas Santos ;
Drumond, Betania Paiva ;
Trindade, Giliane de Souza ;
da Silva-Fernandes, Andre Tavares ;
Siqueira Ferreira, Jaqueline Maria ;
Alves, Pedro Augusto ;
Campos, Rafael Kroon ;
Siqueira, Larissa ;
Bonjardim, Claudio Antonio ;
Peregrino Ferreira, Paulo Cesar ;
Kroon, Erna Geessien .
JOURNAL OF MEDICAL VIROLOGY, 2010, 82 (04) :692-699
[3]   Giant and recurrent orf virus infection in a renal transplant recipient treated with imiquimod [J].
Ara, Mariano ;
Zaballos, Pedro ;
Sanchez, Milagros ;
Querol, Ignacio ;
Zubiri, Maria Luisa ;
Simal, Estrella ;
Horndler, Carlos .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2008, 58 (02) :S39-S40
[4]  
DAMON I., 2007, FIELDS VIROLOGY, P2079
[5]  
GROVES R, 1990, ARCH DERMATOL, V126, P1649, DOI 10.1001/archderm.126.12.1649
[6]  
Haig DM, 1998, VET RES, V29, P311
[7]   Comparative sequence analysis of major envelope protein gene (B2L) of Indian orf viruses isolated from sheep and goats [J].
Hosamani, Madhusudan ;
Bhanuprakash, V. ;
Scagliarini, A. ;
Singh, R. K. .
VETERINARY MICROBIOLOGY, 2006, 116 (04) :317-324
[8]  
Housawi FM, 2010, REV SCI TECH, V28, P1025
[9]   Spatial and Temporal Genetic Homogeneity of Orf Viruses Infecting Japanese Serows (Capricornis crispus) [J].
Inoshima, Yasuo ;
Ito, Mika ;
Ishiguro, Naotaka .
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2010, 72 (06) :701-707
[10]  
Leite-Browning M, 2008, CONTAGIOUS ECTHYMA O