High-efficiency TALEN-based gene editing produces disease-resistant rice

被引：711
作者：
Li, Ting [1 ]
Liu, Bo [1 ]
Spalding, Martin H. [1 ]
Weeks, Donald P. [2 ]
Yang, Bing [1 ]
机构：
[1] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA
[2] Univ Nebraska, Dept Biochem, Lincoln, NE 68583 USA
来源：
NATURE BIOTECHNOLOGY | 2012年 / 30卷 / 05期
基金：
美国国家科学基金会;
关键词：
DOUBLE-STRAND BREAKS; SUSCEPTIBILITY GENE; EFFECTOR NUCLEASES; BACTERIAL-BLIGHT; PROTEINS; KNOCKOUT;
D O I：
10.1038/nbt.2199
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：390 / 392
页数：3
相关论文
共 14 条
  • [1] Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3
    Antony, Ginny
    Zhou, Junhui
    Huang, Sheng
    Li, Ting
    Liu, Bo
    White, Frank
    Yang, Bing
    [J]. PLANT CELL, 2010, 22 (11) : 3864 - 3876
  • [2] Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
    Cermak, Tomas
    Doyle, Erin L.
    Christian, Michelle
    Wang, Li
    Zhang, Yong
    Schmidt, Clarice
    Baller, Joshua A.
    Somia, Nikunj V.
    Bogdanove, Adam J.
    Voytas, Daniel F.
    [J]. NUCLEIC ACIDS RESEARCH, 2011, 39 (12) : e82
  • [3] Sucrose Efflux Mediated by SWEET Proteins as a Key Step for Phloem Transport
    Chen, Li-Qing
    Qu, Xiao-Qing
    Hou, Bi-Huei
    Sosso, Davide
    Osorio, Sonia
    Fernie, Alisdair R.
    Frommer, Wolf B.
    [J]. SCIENCE, 2012, 335 (6065) : 207 - 211
  • [4] Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
    Christian, Michelle
    Cermak, Tomas
    Doyle, Erin L.
    Schmidt, Clarice
    Zhang, Feng
    Hummel, Aaron
    Bogdanove, Adam J.
    Voytas, Daniel F.
    [J]. GENETICS, 2010, 186 (02) : 757 - U476
  • [5] Genetic engineering of human pluripotent cells using TALE nucleases
    Hockemeyer, Dirk
    Wang, Haoyi
    Kiani, Samira
    Lai, Christine S.
    Gao, Qing
    Cassady, John P.
    Cost, Gregory J.
    Zhang, Lei
    Santiago, Yolanda
    Miller, Jeffrey C.
    Zeitler, Bryan
    Cherone, Jennifer M.
    Meng, Xiangdong
    Hinkley, Sarah J.
    Rebar, Edward J.
    Gregory, Philip D.
    Urnov, Fyodor D.
    Jaenisch, Rudolf
    [J]. NATURE BIOTECHNOLOGY, 2011, 29 (08) : 731 - 734
  • [6] Heritable gene targeting in zebrafish using customized TALENs
    Huang, Peng
    Xiao, An
    Zhou, Mingguo
    Zhu, Zuoyan
    Lin, Shuo
    Zhang, Bo
    [J]. NATURE BIOTECHNOLOGY, 2011, 29 (08) : 699 - 700
  • [7] Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
    Li, Ting
    Huang, Sheng
    Zhao, Xuefeng
    Wright, David A.
    Carpenter, Susan
    Spalding, Martin H.
    Weeks, Donald P.
    Yang, Bing
    [J]. NUCLEIC ACIDS RESEARCH, 2011, 39 (14) : 6315 - 6325
  • [8] TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
    Li, Ting
    Huang, Sheng
    Jiang, Wen Zhi
    Wright, David
    Spalding, Martin H.
    Weeks, Donald P.
    Yang, Bing
    [J]. NUCLEIC ACIDS RESEARCH, 2011, 39 (01) : 359 - 372
  • [9] De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
    Mahfouz, Magdy M.
    Li, Lixin
    Shamimuzzaman, Md.
    Wibowo, Anjar
    Fang, Xiaoyun
    Zhu, Jian-Kang
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (06) : 2623 - 2628
  • [10] A TALE nuclease architecture for efficient genome editing
    Miller, Jeffrey C.
    Tan, Siyuan
    Qiao, Guijuan
    Barlow, Kyle A.
    Wang, Jianbin
    Xia, Danny F.
    Meng, Xiangdong
    Paschon, David E.
    Leung, Elo
    Hinkley, Sarah J.
    Dulay, Gladys P.
    Hua, Kevin L.
    Ankoudinova, Irina
    Cost, Gregory J.
    Urnov, Fyodor D.
    Zhang, H. Steve
    Holmes, Michael C.
    Zhang, Lei
    Gregory, Philip D.
    Rebar, Edward J.
    [J]. NATURE BIOTECHNOLOGY, 2011, 29 (02) : 143 - U149
12