Endosulfan and other organochlorine pesticide residues in maternal and cord blood in North Indian population

被引:46
作者
Pathak, Rahul [1 ,2 ]
Suke, Sanvidhan G. [1 ,2 ]
Ahmed, Rafat S. [1 ,2 ]
Tripathi, A. K. [1 ,2 ]
Guleria, Kiran [3 ]
Sharma, C. S. [4 ]
Makhijani, S. D. [4 ]
Mishra, Meenu [4 ]
Banerjee, B. D. [1 ,2 ]
机构
[1] Univ Coll Med Sci, Environm Biochem & Immunol Lab, Dept Biochem, Delhi 110095, India
[2] Univ Delhi, GTB Hosp, Delhi 110095, India
[3] Univ Coll Med Sci, Dept Obstet & Gynaecol, Delhi 110095, India
[4] Minist Environm & Forest, Cent Pollut Control Board, Instrumentat Biolabs, Delhi 110032, India
关键词
organochlorine pesticides; endosulfan; maternal blood; cord blood; North Indian population;
D O I
10.1007/s00128-008-9459-9
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Humans are exposed to various environmental chemicals such as organochlorine pesticide residues, heavy metals, polychlorinatedbiphenyls (PCBs) etc. There is paucity of data regarding the present blood levels of organochlorine residues in North Indian population with reference to reproductive health. The present study was designed to analyze the levels of organochlorine pesticide residues in maternal and cord blood samples of normal healthy women with full term pregnancy to gain insight into the current status of pesticide burden in newborns. Hexachlorocyclohexane (HCH) contributed maximum towards the total organochlorine residues present in maternal and cord blood followed by endosulfan, pp' DDE and pp' DDT being the least. This is also the first report indicating endosulfan levels in this population. Our data indicates a transfer rate of 60-70% of these pesticides from mothers to newborns and this high rate of transfer of pesticides is of great concern as it may adversely affect the growth and development of newborn.
引用
收藏
页码:216 / 219
页数:4
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