VTE Risk Profiles and Prophylaxis in Medical and Surgical Inpatients The Identification of Chinese Hospitalized Patients' Risk Profile for Venous Thromboembolism (DissolVE-2)-A Cross-sectional Study

被引：68

作者：

Zhai, Zhenguo ^{[1
]}

Kan, Quancheng ^{[2
]}

Li, Weimin ^{[3
]}

Qin, Xinyu ^{[4
]}

Qu, Jieming ^{[5
,6
]}

Shi, Yuankai ^{[7
,8
]}

Xu, Yuming ^{[9
,10
]}

Zhang, Zhu ^{[1
,11
]}

Wang, Chen ^{[1
,11
,12
]}

Zhu, Fuyi ^{[13
]}

Jiang, Min ^{[14
]}

Deng, Yingmei ^{[15
]}

Li, Xueqii ^{[16
]}

Geng, Deqin ^{[17
]}

Zhai, Jieming ^{[18
]}

Wang, Caifang ^{[19
]}

Zhang, Junhui ^{[20
]}

Cao, Jie ^{[21
]}

Chen, Shaoyong ^{[22
]}

Li, Gangzhi ^{[23
]}

Wang, Liming ^{[24
]}

Zhang, Yulin ^{[25
]}

Liu, Xiang ^{[26
]}

Zhang, Xiaoju ^{[27
]}

Luo, Xianguo ^{[28
]}

Li, Xia ^{[29
]}

Zhao, Li ^{[30
]}

Zu, Nanwei ^{[31
]}

Lu, Xiaofang ^{[32
]}

Yang, Lan ^{[33
]}

Zhang, Nuofu ^{[34
]}

Pang, Wuyan ^{[35
]}

Ji, Yingqun ^{[36
]}

Yao, Yazhou ^{[37
]}

Sun, Xuhui ^{[38
]}

Xu, Wenda ^{[39
]}

Zhao, Jianqing ^{[40
]}

Leng, Huilin ^{[41
]}

Yu, Zehong ^{[42
]}

Kuang, Guangzhi ^{[43
]}

Huang, Yijiang ^{[44
]}

Chen, Lin ^{[45
]}

Shi, Juhong ^{[46
]}

Xin, Shijie ^{[47
]}

Xiao, Peng ^{[48
]}

Du, Zhiming ^{[49
]}

Wei, Yan ^{[50
]}

Liu, Yongchun ^{[51
]}

Zhang, Chunfang ^{[52
]}

Xu, Yvming ^{[53
]}

机构：

[1] China Japan Friendship Hosp, Natl Clin Res Ctr Resp Dis, Ctr Resp Med, Dept Pulm & Crit Care Med, 2 Yinghua Dongjie, Beijing, Peoples R China

[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Pharm, Zhengzhou, Henan, Peoples R China

[3] Sichuan Univ, West China Hosp, Dept Pulm & Crit Care Med, Chengdu, Sichuan, Peoples R China

[4] Fudan Univ, Zhongshan Hosp, Dept Gen Surg, Shanghai, Peoples R China

[5] Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Dept Resp Med, Shanghai, Peoples R China

[6] Fudan Univ, Huadong Hosp, Dept Resp Med, Shanghai, Peoples R China

[7] Chinese Acad Med Sci, Canc Hosp, Natl Canc Ctr, Dept Med Oncol, Beijing, Peoples R China

[8] Peking Union Med Coll, Beijing Key Lab Clin Study Anticanc Mol Targeted, Beijing, Peoples R China

[9] Sun Yat Sen Univ, Canc Ctr, State Key Lab Oncol South China, Collaborat Innovat Ctr Canc Med,Dept Med Oncol, Guangzhou, Guangdong, Peoples R China

[10] Zhengzhou Univ, Affiliated Hosp 1, Dept Neurol, Zhengzhou, Henan, Peoples R China

[11] Chinese Acad Med Sci, Peking Union Med Coll, Beijing, Peoples R China

[12] Capital Med Univ, Dept Resp Med, Beijing, Peoples R China

[13] Shanxi Fenyang Hosp, Gen Surg Dept, Linfen, Shanxi, Peoples R China

[14] Jiangxi Prov Peoples Hosp, Resp Med Dept, Sheng, Jiangxi, Peoples R China

[15] Capital Med Univ, Xuanwu Hosp, Med Records Dept, Beijing, Peoples R China

[16] Harbin Med Univ, Affiliated Hosp 4, Cardiovasc Med Dept, Harbin, Heilongjiang, Peoples R China

[17] Xuzhou Med Coll, Affiliated Hosp, Neurol Dept, Xuzhou, Jiangsu, Peoples R China

[18] Shanghai Jiao Tong Univ, Sch Med, Ruijin Affiliated Hosp, Resp Med Dept, Shanghai, Peoples R China

[19] Qingyuan Peoples Hosp, Nursing Dept, Qingyuan, Guangdong, Peoples R China

[20] Hebei Univ Engn, Affiliated Hosp, Resp Med Dept, Handan, Hebei, Peoples R China

[21] Tianjin Med Univ, Gen Hosp, Resp Med Dept, Tianjin, Peoples R China

[22] Anshan Cent Hosp, Resp Med Dept, Anshan, Liaoning, Peoples R China

[23] Shuining Cent Hosp, Burn Plast Surg Dept, Tianjin, Peoples R China

[24] Lvliang Peoples Hosp, Orthopaed Dept, Taiyuan, Shanxi, Peoples R China

[25] Yichang First Peoples Hosp, Cadiothorac Surg Dept, Yichang, Hubei, Peoples R China

[26] Xiangtan Cent Hosp, Pharm Dept, Xiangtan, Peoples R China

[27] Henan Prov Peoples Hosp, Resp Med Dept, Zhengzhou, Henan, Peoples R China

[28] First Hosp Qiqihar, Orthopaed Dept, Qiqihar, Heilongjiang, Peoples R China

[29] Shenzhen Longgang Cent Hosp, Oncol Dept, Shenzhen, Peoples R China

[30] China Med Univ, Shengjing Affiliated Hosp, Resp Med Dept, Shenyang, Liaoning, Peoples R China

[31] Second Peoples Hosp Changzhou City, Orthopaed Dept, Changzhou City, Jiangsu, Peoples R China

[32] Capital Med Univ, Beijing Tongren Hosp, Resp Med Dept, Beijing, Peoples R China

[33] Xi An Jiao Tong Univ, Affiliated Hosp 1, Resp Med Dept, Xian, Shaanxi, Peoples R China

[34] Guangzhou Med Univ, Affiliated Hosp 1, Resp Med Dept, Guangzhou, Guangdong, Peoples R China

[35] Henan Univ, Huaihe Hosp, Endocrinol Dept, Kaifeng, Henan, Peoples R China

[36] Dalian Med Univ, Affiliated Hosp 1, Resp Med Dept, Dalian, Liaoning, Peoples R China

[37] Baoji Cent Hosp, Yazhou Yao Hematol Dept, Baoji, Shanxi, Peoples R China

[38] Taizhou Peoples Hosp, Inst Off, Taizhou, Jiangsu, Peoples R China

[39] Nanchang Peoples Hosp, Crit Care Dept, Nanchang, Jiangxi, Peoples R China

[40] Hebei Inst North, Affiliated Hosp 1, Resp Med Dept, Zhangjiakou, Hebei, Peoples R China

[41] Yichun Peoples Hosp, Sci & Educ Dept, Yichun, Jiangxi, Peoples R China

[42] Jiangmen Peoples Hosp, Cardiovasc Med Dept, Jiangmen, Guangdong, Peoples R China

[43] Kaiping Cent Hosp, Orthopaed Dept, Jiangmen, Guangdong, Peoples R China

[44] Peoples Hosp Hainan Prov, Resp Med Dept, Haikou, Hainan, Peoples R China

[45] Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China

[46] China Acad Med Sci, Beijing Union Med Coll Hosp, Resp Med Dept, Beijing, Peoples R China

[47] China Med Univ, Affiliated Hosp 1, Vasc Surg Dept, Heping, Peoples R China

[48] Guiyang Med Coll, Affiliated Hosp, Sci & Educ Dept, Guiyang, Guizhou, Peoples R China

[49] Sun Yat Sen Univ, Affiliated Hosp 1, Cardiovasc Med Dept, Guangzhou, Guangdong, Peoples R China

[50] Hengshui Peoples Hosp, Neurol Dept, Hengshui, Hebei, Peoples R China

来源：

CHEST | 2019年 / 155卷 / 01期

关键词：

China; prophylaxis; risk profile; VTE; CARE SETTING ENDORSE; PREVENTION; THROMBOPROPHYLAXIS; EPIDEMIOLOGY;

D O I：

10.1016/j.chest.2018.09.020

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

BACKGROUND: Limited data exist on VTE risk and prophylaxis in Chinese inpatients. The Identification of Chinese Hospitalized Patients' Risk Profile for Venous Thromboembolism-2 (DissolVE-2), a nationwide, multicenter, cross-sectional study, was therefore designed to investigate prevalence of VTE risks and evaluate VTE prophylaxis implementation compliant with the latest prophylaxis guidelines (American College of Chest Physicians [CHEST], 9th edition). METHODS: Adults admitted (>= 72 h) to 60 urban, tertiary Chinese hospitals due to acute medical conditions or surgery from March to September 2016 were assessed for VTE risk. Risk assessments were made by using the Padua Prediction Scoring or Caprini Risk Assessment model, risk factors, and prophylaxis based on the CHEST guidelines, 9th edition. RESULTS: A total of 13,609 patients (6,986 surgical and 6,623 medical) were analyzed. VTE risk in surgical inpatients was categorized as low (13.9%; 95% CI, 13.1-14.7), moderate (32.7%; 95% CI, 31.6-33.8), and high (53.4%; 95% CI, 52.2-54.6); risk in medical patients was categorized as low (63.4%; 95% CI, 62.2-64.6) and high (36.6%; 95% CI, 35.4-37.8). Major risk factors in surgical and medical patients were major open surgery (52.6%) and acute infection (42.2%), respectively. Overall rate of any prophylaxis and appropriate prophylactic method was 14.3% (19.0% vs 9.3%) and 10.3% (11.8% vs 6.0%) in surgical and medical patients. CONCLUSIONS: A large proportion of hospitalized patients reported VTE risk and low rate of CHEST-recommended prophylaxis. The data highlight the insufficient management of VTE risk and show the great potential for improving physicians' awareness and current practices across China.

引用

页码：114 / 122

页数：9

共 26 条

[1] Assessment of Venous Thromboembolism Risk and Adequacy of Prophylaxis in Selected Acute Care Medical Centres in Arabian Gulf States: Results from the ENDORSE Study [J].