Integrated natural deep eutectic solvent and pulse-ultrasonication for efficient extraction of crocins from gardenia fruits (Gardenia jasminoides Ellis) and its bioactivities

被引：167

作者：

Huang, Hao ^{[1
]}

Zhu, Yingjie ^{[1
]}

Fu, Xizhe ^{[1
]}

Zou, Ying ^{[4
]}

Li, Qunhe ^{[4
]}

Luo, Zisheng ^{[1
,2
,3
]}

机构：

[1] Zhejiang Univ, Coll Biosyst Engn & Food Sci, Key Lab Agroprod Postharvest Handling,Zhejiang Ke, Minist Agr & Rural Affairs,Natl Local Joint Engn, Hangzhou, Peoples R China

[2] Zhejiang Univ, Fuli Inst Food Sci, Hangzhou, Peoples R China

[3] Zhejiang Univ, Ningbo Res Inst, Hangzhou, Peoples R China

[4] Wenzhou Vocat Coll Sci & Technol, Wenzhou, Peoples R China

来源：

FOOD CHEMISTRY | 2022年 / 380卷

关键词：

Natural deep eutectic solvent; Pulse-ultrasonication; Crocins; Gardenia fruits; ULTRASOUND-ASSISTED EXTRACTION; VISCOSITY; CAROTENOIDS; ANTIOXIDANT;

D O I：

10.1016/j.foodchem.2022.132216

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

This study proposed natural deep eutectic solvent (NADES) based pulse-ultrasonication-assisted extraction (PUAE) for green recovery of crocins from gardenia fruits (Gardenia jasminoides Ellis). Choline chloride-1,2-propylene glycol (ChCl-PG, 1:2.5, mol/mol) with 35 % (v/v) water content was tailor-made to obtain the highest extraction efficiency with high surface tension, polarity, conductivity, pH, and low viscosity, density for affinity-based extraction of crocins. The optimized P-UAE conditions (extraction time 120 s, ultrasonic power 400 W, solvent-to-solid ratio 40 mL g(-1), extraction temperature 35 celcius) led to the maximum yield of crocins (36.97 mg g(-1) DW). The second-order kinetic model was fitted to the extraction process and the synergistic effect was verified by SEM and FTIR. The crocetin was identified as the main compound by UPLC-Triple-TOF/MS. The antiglycative effect and protective effect on DNA indicated the bioactive activities of crocins. Therefore, the ChCl-PG based P-UAE could serve as a green strategy to effectively extract crocins from gardenia fruits.

引用

页数：11

共 46 条

[1] Application of hole theory to the viscosity of ionic and molecular liquids [J].

Abbott, AP .

CHEMPHYSCHEM, 2004, 5 (08) :1242-1246

[2] Choline chloride-based deep eutectic solvents as green extractants for the isolation of phenolic compounds from biomass [J].

Alam, Md. Asraful ;

Muhammad, Gul ;

Khan, M. Nuruzzaman ;

Mofijur, M. ;

Lv, Yongkun ;

Xiong, Wenlong ;

Xu, Jingliang .

JOURNAL OF CLEANER PRODUCTION, 2021, 309

[3] Troxerutin imparts preservative effects on albumin by preventing Maillard reaction-mediated early and advanced glycation modification [J].

Awasthi, Saurabh ;

Ravi, Aravind ;

Saraswathi, N. T. .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 35 (12) :2681-2687

[4] Recent advances in scaling-up of non-conventional extraction techniques: Learning from successes and failures [J].

Belwal, Tarun ;

Chemat, Farid ;

Venskutonis, Petras Rimantas ;

Cravotto, Giancarlo ;

Jaiswal, Durgesh Kumar ;

Bhatt, Indra Dutt ;

Devkota, Hari Prasad ;

Luo, Zisheng .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2020, 127

[5] Optimization model for ultrasonic-assisted and scale-up extraction of anthocyanins from Pyrus communis 'Starkrimson' fruit peel [J].

Belwal, Tarun ;

Huang, Hao ;

Li, Li ;

Duan, Zhenhua ;

Zhang, Xuebing ;

Aalim, Halah ;

Luo, Zisheng .

FOOD CHEMISTRY, 2019, 297

[6] Crocin, the main active saffron constituent, mitigates dichlorvos-induced oxidative stress and apoptosis in HCT-116 cells [J].

Ben Salem, Intidhar ;

Boussabbeh, Manel ;

Kantaoui, Hiba ;

Bacha, Hassen ;

Abid-Essefi, Salwa .

BIOMEDICINE & PHARMACOTHERAPY, 2016, 82 :65-71

[7] The impact of high-pressure processing on the polyphenol profile and anti-glycaemic, anti-hypertensive and anti-cholinergic activities of extracts obtained from kiwiberry (Actinidia arguta) fruits [J].

Blaszczak, Wioletta ;

Latocha, Piotr ;

Jez, Maja ;

Wiczkowski, Wieslaw .

FOOD CHEMISTRY, 2021, 343

[8] Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review [J].

Chemat, Farid ;

Rombaut, Natacha ;

Sicaire, Anne-Gaelle ;

Meullemiestre, Alice ;

Fabiano-Tixier, Anne-Sylvie ;

Abert-Vian, Maryline .

ULTRASONICS SONOCHEMISTRY, 2017, 34 :540-560

[9] Extraction techniques with deep eutectic solvents [J].

Cunha, Sara C. ;

Fernandes, Jose O. .

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2018, 105 :225-239

[10] Natural Deep Eutectic Solvents as a New Extraction Media for Phenolic Metabolites in Carthamus tinctorius L. [J].

Dai, Yuntao ;

Witkamp, Geert-Jan ;

Verpoorte, Robert ;

Choi, Young Hae .

ANALYTICAL CHEMISTRY, 2013, 85 (13) :6272-6278

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