Seventeen on inflammation

被引:5
作者
Dong, Chen [1 ,2 ]
机构
[1] Tsinghua Univ, Inst Immunol, Beijing, Peoples R China
[2] Tsinghua Univ, Sch Med, Beijing, Peoples R China
关键词
CELLS; DISTINCT; LINEAGE;
D O I
10.1038/s41590-020-0649-x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In October 2005, we, alongside the laboratory of Casey Weaver, identified a third type of helper T cells that produce the cytokine IL-17, important for the regulation of tissue inflammation.
引用
收藏
页码:821 / 822
页数:2
相关论文
共 8 条
[1]   Regulation of immune and autoimmune responses by ICOS [J].
Dong, C ;
Nurieva, RI .
JOURNAL OF AUTOIMMUNITY, 2003, 21 (03) :255-260
[2]   ICOS co-stimulatory receptor is essential for T-cell activation and function [J].
Dong, C ;
Juedes, AE ;
Temann, UA ;
Shresta, S ;
Allison, JP ;
Ruddle, NH ;
Flavell, RA .
NATURE, 2001, 409 (6816) :97-101
[3]   TH 17 cells in development:: an updated view of their molecular identity and genetic programming [J].
Dong, Chen .
NATURE REVIEWS IMMUNOLOGY, 2008, 8 (05) :337-348
[4]   Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages [J].
Harrington, LE ;
Hatton, RD ;
Mangan, PR ;
Turner, H ;
Murphy, TL ;
Murphy, KM ;
Weaver, CT .
NATURE IMMUNOLOGY, 2005, 6 (11) :1123-1132
[5]   Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases [J].
Lai, Yuping ;
Dong, Chen .
INTERNATIONAL IMMUNOLOGY, 2016, 28 (04) :181-188
[6]   IL-23 drives a pathogenic T cell population that induces autoimmune inflammation [J].
Langrish, CL ;
Chen, Y ;
Blumenschein, WM ;
Mattson, J ;
Basham, B ;
Sedgwick, JD ;
McClanahan, T ;
Kastelein, RA ;
Cua, DJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (02) :233-240
[7]   Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages [J].
Nurieva, Roza I. ;
Chung, Yeonseok ;
Hwang, Daehee ;
Yang, Xuexian O. ;
Kang, Hong Soon ;
Ma, Li ;
Wang, Yi-Hong ;
Watowich, Stephanie S. ;
Jetten, Anton M. ;
Tian, Qiang ;
Dong, Chen .
IMMUNITY, 2008, 29 (01) :138-149
[8]   A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 [J].
Park, H ;
Li, ZX ;
Yang, XO ;
Chang, SH ;
Nurieva, R ;
Wang, YH ;
Wang, Y ;
Hood, L ;
Zhu, Z ;
Tian, Q ;
Dong, C .
NATURE IMMUNOLOGY, 2005, 6 (11) :1133-1141