Protein-protein interactions in the archaeal core replisome

被引：8
|
作者：
MacNeill, Stuart A. [1 ]
机构：
[1] Univ St Andrews, St Andrews KY16 9TF, Fife, Scotland
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 2011年 / 39卷
基金：
英国惠康基金;
关键词：
archaeon; chromosome replication; DNA replication; protein-protein interaction; replication machinery; replisome; MCM HELICASE ACTIVITY; REPLICATION FACTOR-C; CRENARCHAEON SULFOLOBUS-SOLFATARICUS; MINICHROMOSOME MAINTENANCE HELICASE; CLAMP-LOADER COMPLEX; CELL NUCLEAR ANTIGEN; DNA-REPLICATION; PYROCOCCUS-FURIOSUS; HETEROTRIMERIC PCNA; CDC6; PROTEIN;
D O I：
10.1042/BST0390163
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Most of the core components of the archaeal chromosomal DNA replication apparatus share significant protein sequence similarity with eukaryotic replication factors, making the Archaea an excellent model system for understanding the biology of chromosome replication in eukaryotes. The present review summarizes current knowledge of how the core components of the archaeal chromosome replication apparatus interact with one another to perform their essential functions.
引用
收藏
页码：163 / 168
页数：6
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