Biodegradable polymer scaffold for tissue engineering

被引:21
作者
Tateishi, T [1 ]
Chen, G [1 ]
机构
[1] Natl Inst Mat Sci, Ctr Biomat, Tsukuba, Ibaraki 3050044, Japan
来源
ASBM6: ADVANCED BIOMATERIALS VI | 2005年 / 288-289卷
关键词
biodegradable polymer; tissue engineering; hybrid sponge; hybrid mesh; articular cartilage;
D O I
10.4028/www.scientific.net/KEM.288-289.59
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A new method for the preparation of biodegradable porous scaffolds has been developed by using pre-prepared ice particulates as porogen material. A novel kind of hybrid biodegradable porous scaffold has been developed by forming collagen microsponges in the pores or interstices of a synthetic polymer sponge or mesh. A hybrid sponge of synthetic polymer, collagen and hydroxyapatite has been developed for hard tissue engineering. Bovine articular cartilage-like tissue has been engineered by culturing chondrocytes in the PLGA-collagen scaffolds.
引用
收藏
页码:59 / 62
页数:4
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