Dual PI3K/mTOR inhibition in combination with inhibition of autophagy to improve treatment response for BCR-ABL independent mechanisms of TKI-resistance in CML

被引:0
作者
Mitchell, R. [1 ]
Allan, E. K. [2 ]
Baquero, P. [1 ]
Mukhopadhyay, A. [3 ]
Clark, R. [4 ]
Mitra, S. [5 ]
Druker, B. J. [6 ]
Salomoni, P. [7 ]
Calabretta, B. [8 ]
Chan, E. [9 ]
Nicolini, F. E. [10 ]
Holyoake, T. L. [3 ]
Helgason, G. V. [1 ]
机构
[1] Univ Glasgow, Inst Canc Sci, Coll Med Vet & Life Sci, Wolfson Wohl Canc Res Ctr, Glasgow G12 8QQ, Lanark, Scotland
[2] Gartnavel Royal Hosp, Scottish Natl Blood Transfus Serv, Glasgow, Lanark, Scotland
[3] Univ Glasgow, Inst Canc Sci, Coll Med Vet & Life Sci, Paul OGorman Leukaemia Res Ctr, Glasgow G12 8QQ, Lanark, Scotland
[4] Univ Liverpool, Dept Mol & Clin Canc Med, Sect Haematol, Liverpool L69 3BX, Merseyside, England
[5] Milton Keynes Hosp NHS Fdn Trust, Dept Haematol, Milton Keynes, Bucks, England
[6] Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97201 USA
[7] UCL Canc Inst, Samantha Dickson Brain Canc Unit, London, England
[8] Thomas Jefferson Univ, Kimmel Canc Ctr, Dept Canc Biol, Philadelphia, PA 19107 USA
[9] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow, Lanark, Scotland
[10] Hop Edouard Herriot, Hematol Clin, Lyon, France
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
218
引用
收藏
页码:88 / 89
页数:2
相关论文
empty
未找到相关数据