Radical Intramolecular Arylation of Pyridinium Salts: A Straightforward Entry to 7-Hydroxypyrido[2,1-a]isoquinolinylium Salts

被引：13

作者：

Castillo, Rafael R. ^{[1
]}

Burgos, Carolina ^{[1
]}

Vaquero, Juan J. ^{[1
]}

Alvarez-Builla, Julio ^{[1
]}

机构：

[1] Univ Alcala de Henares, Dept Quim Organ, E-28871 Alcala De Henares, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 2011卷 / 03期

关键词：

Radical reactions; Nitrogen heterocycles; Intramolecular arylation; PROMOTED AROMATIC ALKYLATIONS; ARYL BROMIDES; CYCLIZATION; SUBSTITUTION; N-2'-PYRIDYLAMINIDE; TODDAQUINOLINE; ADDITIONS; BIARYLS;

D O I：

10.1002/ejoc.201001071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 7-hydroxypyrido[2,1-a]isoquinolinylium salts can be achieved in moderate yields by intramolecular radical arylation of pyridinium salts obtained from substituted pyridines and o-bromophenacyl bromides.

引用

页码：619 / 628

页数：10

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