Hydrogels with incorporated graphene oxide as light-addressable actuator materials for cell culture environments in lab-on-chip systems

被引：8

作者：

Breuer, L. ^{[1
]}

Raue, M. ^{[2
]}

Strobel, M. ^{[1
]}

Mang, T. ^{[2
]}

Schoening, M. J. ^{[1
,3
]}

Thoelen, R. ^{[4
]}

Wagner, T. ^{[1
,3
]}

机构：

[1] Aachen Univ Appl Sci, Inst Nano & Biotechnol INB, D-52428 Julich, Germany

[2] Aachen Univ Appl Sci, Inst Appl Polymer Chem IAP, D-52428 Julich, Germany

[3] Res Ctr Julich, Peter Grunberg Inst PGI 8, D-52428 Julich, Germany

[4] Hasselt Univ, Inst Mat Res IMO, B-3590 Diepenbeek, Belgium

来源：

PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE | 2016年 / 213卷 / 06期

关键词：

actuators; cell cultures; graphene oxide; hydrogels; lab-on-chip systems; photopolymerization; NANOCOMPOSITE HYDROGELS; SENSITIVE HYDROGELS; MICROFLUIDICS; VALVES;

D O I：

10.1002/pssa.201533056

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Graphene oxide (GO) nanoparticles were incorporated in temperature-sensitive Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels. The nanoparticles increase the light absorption and convert light energy into heat efficiently. Thus, the hydrogels with GO can be stimulated spatially resolved by illumination as it was demonstrated by IR thermography. The temporal progression of the temperature maximum was detected for different concentrations of GO within the polymer network. Furthermore, the compatibility of PNIPAAm hydrogels with GO and cell cultures was investigated. For this purpose, culture medium was incubated with hydrogels containing GO and the viability and morphology of chinese hamster ovary (CHO) cells was examined after several days of culturing in presence of this medium. (C) 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1520 / 1525

页数：6

共 3 条

[1] Towards light-addressable flow control: Responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels
Breuer, Lars
Pilas, Johanna
Guthmann, Eric
Schoening, Michael J.
Thoelen, Ronald
Wagner, Torsten
SENSORS AND ACTUATORS B-CHEMICAL, 2019, 288 : 579 - 585
[2] Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography
Breuer, Lars
Mang, Thomas
Schoening, Michael J.
Thoelen, Ronald
Wagner, Torsten
SENSORS AND ACTUATORS A-PHYSICAL, 2017, 268 : 126 - 132
[3] Actively Driven Light-Addressable Sensor/Actuator System for Automated pH Control for the Integration in Lab-On-A-Chip (LoC) Platforms
Welden, Rene
Das, Anirban
Krause, Steffi
Schoening, Michael J.
Wagner, Patrick H.
Wagner, Torsten
ACS SENSORS, 2024, 9 (03) : 1533 - 1544

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