Non-invasive image acquisition and advanced processing in optical bioimaging

被引：75

作者：

Farkas, DL ^{[1
]}

Du, CW ^{[1
]}

Fisher, GW ^{[1
]}

Lau, C ^{[1
]}

Niu, WH ^{[1
]}

Wachman, ES ^{[1
]}

Levenson, RM ^{[1
]}

机构：

[1] Carnegie Mellon Univ, Ctr Light Microscope Imaging & Biotechnol, Pittsburgh, PA 15213 USA

来源：

COMPUTERIZED MEDICAL IMAGING AND GRAPHICS | 1998年 / 22卷 / 02期

基金：

美国国家科学基金会;

关键词：

fluorescence; tomography; spectral imaging; acousto-optic tunable filters; Fourier spectroscopy; microscopy; mesoscopy; processing; reconstruction; back-projection;

D O I：

10.1016/S0895-6111(98)00011-1

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Light is a most versatile tool for investigating biological systems and phenomena; the range, non-destructiveness, spatial discrimination and speed of optical imaging are all important for investigating structure and function at the cellular, tissue or even whole organism level. In live biological imaging, where the technological requirements are heightened, other features of light, such as coherence and wavelength, are used to generate the additional contrast and resolution needed. We report here recent improvements in our ability to image biological specimens optically, focusing on (a) spectral resolution and the related image processing issues, and (b) tomographic three-dimensional fluorescence imaging in vivo. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：89 / 102

页数：14

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