Cortisol secretion in the elderly. Influence of age, sex and cardiovascular disease in a Chinese population

被引：26
作者：
Zhao, ZY
Lu, FH
Xie, Y
Fu, YR
Bogdan, A
Touitou, Y
机构：
[1] Univ Paris 06, Dept Biochem, F-75013 Paris, France
[2] Shandong Acad Med Sci, Antisenil Res Ctr Shandong, Jinan 250062, Peoples R China
来源：
STEROIDS | 2003年 / 68卷 / 06期
关键词：
cortisol; age; sex; cardiovascular disease;
D O I：
10.1016/S0039-128X(03)00083-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Adrenal function and aging have been the object of intense interest in recent years. In this study we analyzed morning (08:00 h) serum cortisol concentrations from a sample of Chinese subjects aged from 31 to 110 years. These levels differed according to age, health status and sex, although the sex difference was confirmed only among the healthy elderly. These results suggest that age (older than 60 years), disease and male sex are associated with increased morning serum cortisol levels in a Chinese population. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码：551 / 555
页数：5
相关论文
共 30 条
[1]   Is melatonin circadian rhythm a physiological feature associated with healthy longevity?: A study of long-living subjects and their progeny [J].
Cugini, P ;
Touitou, Y ;
Bogdan, A ;
Auzéby, A ;
Pellegrino, AM ;
Fontana, S ;
Vacca, K ;
Di Siena, G ;
De Rosa, R ;
Zannella, FP ;
Zannella, P ;
Zannella, A ;
Sepe, FA ;
Sepe, L .
CHRONOBIOLOGY INTERNATIONAL, 2001, 18 (01) :99-107
[2]   Profiles of endogenous circulating cortisol and bone mineral density in healthy elderly men [J].
Dennison, E ;
Hindmarsh, P ;
Fall, C ;
Kellingray, S ;
Barker, D ;
Phillips, D ;
Cooper, C .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (09) :3058-3063
[3]   Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging [J].
Ferrari, E ;
Casarotti, D ;
Muzzoni, B ;
Albertelli, N ;
Cravello, L ;
Fioravanti, M ;
Solerte, SB ;
Magri, F .
BRAIN RESEARCH REVIEWS, 2001, 37 (1-3) :294-300
[4]   Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia [J].
Ferrari, E ;
Arcaini, A ;
Gornati, R ;
Pelanconi, L ;
Cravello, L ;
Fioravanti, M ;
Solerte, SB ;
Magri, F .
EXPERIMENTAL GERONTOLOGY, 2000, 35 (9-10) :1239-1250
[5]   Age-related changes of the hypothalamic-pituitary-adrenal axis: pathophysiological correlates [J].
Ferrari, E ;
Cravello, L ;
Muzzoni, B ;
Casarotti, D ;
Paltro, M ;
Solerte, SB ;
Fioravanti, M ;
Cuzzoni, G ;
Pontiggia, B ;
Magri, F .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2001, 144 (04) :319-329
[6]   ASSESSMENT OF HYPOTHALAMIC-PITUITARY-ADRENAL FUNCTION IN GERIATRIC AGE GROUP [J].
FRIEDMAN, M ;
GREEN, MF ;
SHARLAND, DE .
JOURNALS OF GERONTOLOGY, 1969, 24 (03) :292-&
[7]   Endocrine aspects of ageing in the male [J].
Gooren, LJG .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1998, 145 (1-2) :153-159
[8]   HYPOTHALAMIC-PITUITARY-ADRENAL FUNCTION IN ELDERLY [J].
GREEN, MF ;
FRIEDMAN, M .
GERONTOLOGIA CLINICA, 1968, 10 (06) :334-&
[9]   Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men [J].
Gusenoff, JA ;
Harman, SM ;
Veldhuis, JD ;
Jayme, JJ ;
St Clair, C ;
Münzer, T ;
Christmas, C ;
O'Connor, KG ;
Stevens, TE ;
Bellantoni, MF ;
Pabst, K ;
Blackman, MR .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2001, 280 (04) :E616-E625
[10]   DIFFERENCES AND SIMILARITIES AMONG CIRCADIAN CHARACTERISTICS OF PLASMA-RENIN ACTIVITY IN HEALTHY-YOUNG WOMEN IN JAPAN AND THE UNITED-STATES [J].
KAWASAKI, T ;
UENO, M ;
UEZONO, K ;
MATSUOKA, M ;
OMAE, T ;
HALBERG, F ;
WENDT, H ;
TAGGETTANDERSON, MA ;
HAUS, E .
AMERICAN JOURNAL OF MEDICINE, 1980, 68 (01) :91-96
123