Multimodality treatment for localized gastro-oesophageal cancer

被引:13
作者
Okines, A. F. C.
Cunningham, D.
机构
[1] Royal Marsden Hosp, Surrey, England
[2] Royal Marsden Hosp, London SW3 6JJ, England
关键词
adjuvant; cardia; chemoradiation; chemotherapy; neoadjuvant; oesophagogastric junction; perioperative; PHASE-III TRIAL; SQUAMOUS-CELL CARCINOMA; RESECTED GASTRIC-CANCER; ADJUVANT CHEMOTHERAPY; ESOPHAGEAL-CARCINOMA; RANDOMIZED-TRIAL; CLINICAL-TRIAL; SURGERY; CHEMORADIOTHERAPY; ADENOCARCINOMA;
D O I
10.1093/annonc/mdq282
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Targeted agents are currently under evaluation in localized oesophagogastric cancer, with translational sub-studies attempting to define which patients may benefit from the addition of these high cost drugs.
引用
收藏
页码:286 / 293
页数:8
相关论文
共 43 条
[1]   Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer [J].
Allum, William H. ;
Stenning, Sally P. ;
Bancewicz, John ;
Clark, Peter I. ;
Langley, Ruth E. .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (30) :5062-5067
[2]  
[Anonymous], 2009, J CLIN ONCOL S
[3]  
APINOP C, 1994, HEPATO-GASTROENTEROL, V41, P391
[4]   Adjuvant chemotherapy in gastric cancer: 5-year results of a randomised study by the Italian Trials in Medical Oncology (ITMO) Group [J].
Bajetta, E ;
Buzzoni, R ;
Mariani, L ;
Beretta, E ;
Bozzetti, F ;
Bordogna, G ;
Aitini, E ;
Fava, S ;
Schieppati, G ;
Pinotti, G ;
Visini, M ;
Ianniello, G ;
Di Bartolomeo, M .
ANNALS OF ONCOLOGY, 2002, 13 (02) :299-307
[5]  
Bancewicz J, 2002, LANCET, V359, P1727
[6]  
Bedenne L, 2007, J CLIN ONCOL, V25, P1160, DOI 10.1200/JCO.2005.04.7118
[7]  
Boige V, 2007, J CLIN ONCOL, V25
[8]   Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus [J].
Bosset, JF ;
Gignoux, M ;
Triboulet, JP ;
Tiret, E ;
Mantion, G ;
Elias, D ;
Lozach, P ;
Ollier, JC ;
Pavy, JJ ;
Mercier, M ;
Sahmoud, T .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (03) :161-167
[9]   Adjuvant chemotherapy with 5-fluorouracil and cisplatin compared with surgery alone for gastric cancer:: 7-year results of the FFCD randomized phase III trial (8801) [J].
Bouché, O ;
Ychou, M ;
Burtin, P ;
Bedenne, L ;
Ducreux, M ;
Lebreton, G ;
Baulieux, J ;
Nordlinger, B ;
Martin, C ;
Seitz, JF ;
Tigaud, JM ;
Echinard, E ;
Stremsdoerfer, N ;
Milan, C ;
Rougier, P .
ANNALS OF ONCOLOGY, 2005, 16 (09) :1488-1497
[10]   Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial [J].
Burmeister, BH ;
Smithers, BM ;
Gebski, V ;
Fitzgerald, L ;
Simes, RJ ;
Devitt, P ;
Ackland, S ;
Gotley, DC ;
Joseph, D ;
Millar, J ;
North, J ;
Walpole, ET ;
Denham, JW .
LANCET ONCOLOGY, 2005, 6 (09) :659-668