Nanotechnology against COVID-19: Immunization, diagnostic and therapeutic studies

被引：27

作者：

Hasanzadeh, Akbar ^{[1
,2
]}

Alamdaran, Masoomeh ^{[1
,2
]}

Ahmadi, Sepideh ^{[3
,4
]}

Nourizadeh, Helena ^{[1
,2
]}

Bagherzadeh, Mohammad Aref ^{[5
,6
]}

Jahromi, Mirza Ali Mofazzal ^{[6
,7
,8
]}

Simon, Perikles ^{[9
]}

Karimi, Mahdi ^{[1
,2
,10
]}

Hamblin, Michael R. ^{[10
,11
,12
]}

机构：

[1] Iran Univ Med Sci, Cellular & Mol Res Ctr, Tehran, Iran

[2] Iran Univ Med Sci, Fac Adv Technol Med, Dept Med Nanotechnol, Tehran, Iran

[3] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Biotechnol, Student Res Comm, Tehran, Iran

[4] Shahid Beheshti Univ Med Sci, Cellular & Mol Biol Res Ctr, Tehran, Iran

[5] Jahrom Univ Med Sci, Student Res Comm, Jahrom, Iran

[6] Jahrom Univ Med Sci, Sch Med, Dept Immunol, Jahrom, Iran

[7] Jahrom Univ Med Sci, Sch Med, Dept Adv Med Sci & Technol, Jahrom, Iran

[8] Jahrom Univ Med Sci, Sch Med, Res Ctr Noncommunicable Dis, Jahrom, Iran

[9] Johannes Gutenberg Univ Mainz, Dept Sport Med Dis Prevent & Rehabil, Fac Social Sci Media & Sport, Mainz, Germany

[10] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA

[11] Harvard Med Sch, Dept Dermatol, Boston, MA 02115 USA

[12] Harvard MIT Div Hlth Sci & Technol, Cambridge, MA 02139 USA

来源：

JOURNAL OF CONTROLLED RELEASE | 2021年 / 336卷

关键词：

Nanotechnology; Nanovaccine; Diagnosis; SARS-CoV-2; COVID-19; ACUTE RESPIRATORY SYNDROME; HERPES-SIMPLEX-VIRUS; NANOSTRUCTURED LIPID CARRIERS; DRUG-DELIVERY SYSTEMS; B SURFACE-ANTIGEN; MAGNETIC NANOPARTICLES; SELENIUM NANOPARTICLES; BIODEGRADABLE NANOPARTICLES; SILVER NANOPARTICLES; GOLD NANOPARTICLES;

D O I：

10.1016/j.jconrel.2021.06.036

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020 soon led to the global pandemic of Coronavirus Disease 2019 (COVID-19). Since then, the clinical and scientific communities have been closely collaborating to develop effective strategies for controlling the ongoing pandemic. The game-changing fields of recent years, nanotechnology and nanomedicine have the potential to not only design new approaches, but also to improve existing methods for the fight against COVID-19. Nanomaterials can be used in the development of highly efficient, reusable personal protective equipment, and antiviral nano-coatings in public settings could prevent the spread of SARS-CoV-2. Smart nanocarriers have accelerated the design of several therapeutic, prophylactic, or immune-mediated approaches against COVID-19. Some nanovaccines have even entered Phase I./II. clinical trials. Several rapid and cost-effective COVID-19 diagnostic techniques have also been devised based on nanobiosensors, lab-on-a-chip systems, or nanopore technology. Here, we provide an overview of the emerging role of nanotechnology in the prevention, diagnosis, and treatment of COVID-19.

引用

页码：354 / 374

页数：21

共 320 条

[1]

ABBOTT TR, 2020, DEV CRISPR PROPHYLAC

[2] The COVID-19 pandemic, psychological stress during pregnancy, and risk of neurodevelopmental disorders in offspring: a neglected consequence [J].