Enhanced antimicrobial and anticancer properties of ZnO and TiO2 nanocomposites

被引:36
作者
Chakra, C. H. Shilpa [1 ]
Rajendar, V. [2 ]
Rao, K. Venkateswara [3 ]
Kumar, Mirgender [2 ]
机构
[1] Jawaharlal Nehru Technol Univ Hyderabad, Ctr Nanosci & Technol, Inst Sci & Technol, Hyderabad 500085, Telangana, India
[2] Yeungnam Univ, Dept Elect Engn, Gyongsan 38541, Gyeongsangbuk D, South Korea
[3] Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA
关键词
Nanocomposite; Zinc oxide; Titanium dioxide; Nanoparticles; Anticancer; Antibacterial; METAL-OXIDE NANOCOMPOSITES; TITANIUM-DIOXIDE; ANTIBACTERIAL PROPERTIES; NANOPARTICLES; SUSPENSIONS;
D O I
10.1007/s13205-017-0731-8
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The study describes the antibacterial and anticancer activities of a nanocomposite prepared by mixing zinc oxide and titanium dioxide nanoparticles. The particle mixtures were analyzed by X-ray diffraction, Field emission scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, and dynamic light scattering techniques. Thus, analyzed samples were subject to disc diffusion method at various concentrations to analyze their antibacterial activities against two Gram-positive and two Gram-negative bacteria. The same samples were then analyzed for their anticancer activities on four different cell lines. The results indicate a synergistic effect of the nanocomposite on both antibacterial and anticancer properties when compared to their individual counterparts.
引用
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页数:8
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