Factors predicting successful discontinuation of continuous renal replacement therapy

被引：41

作者：

Katayama, S. ^{[1
]}

Uchino, S. ^{[2
]}

Uji, M. ^{[3
]}

Ohnuma, T. ^{[4
]}

Namba, Y. ^{[5
]}

Kawarazaki, H. ^{[6
]}

Toki, N. ^{[7
]}

Takeda, K. ^{[8
]}

Yasuda, H. ^{[9
]}

Izawa, J. ^{[2
]}

Tokuhira, N. ^{[10
]}

Nagata, I. ^{[11
]}

机构：

[1] Tokyo Womens Med Univ, Dept Emergency Med, Asahi Gen Hosp, Chiba, Japan

[2] Jikei Univ, Sch Med, Dept Anesthesiol, Intens Care Unit, Tokyo, Japan

[3] Osaka Univ Hosp, Intens Care Unit, Osaka, Japan

[4] Jichi Med Univ, Saitama Med Ctr, Dept Anesthesiol, Intens Care Unit, Saitama, Japan

[5] Showa Univ, Fujigaoka Hosp, Dept Emergency & Crit Care, Kanagawa, Japan

[6] St Marianna Univ, Sch Med, Dept Hypertens & Nephrol, Kawasaki, Kanagawa, Japan

[7] Tokyo Metropolitan Tama Med Ctr, Dept Internal Med, Tokyo, Japan

[8] Hyogo Coll Med, Div Intens Care Med, Nishinomiya, Hyogo, Japan

[9] Japanese Red Cross Musashino Hosp, Dept Emergency & Crit Care Med, Intens Care Unit, Tokyo, Japan

[10] Kyoto Prefectural Univ Med, Univ Hosp, Div Intens Care, Kyoto, Japan

[11] Kanto Rosai Hosp, Dept Emergency, Kawasaki, Kanagawa, Japan

来源：

ANAESTHESIA AND INTENSIVE CARE | 2016年 / 44卷 / 04期

关键词：

acute kidney injury; continuous renal replacement therapy; creatinine level; urine output; CRITICALLY-ILL PATIENTS; RISK-FACTORS; FAILURE; EXTUBATION; MORTALITY; SUPPORT; SCORE;

D O I：

10.1177/0310057X1604400401

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

This multicentre, retrospective observational study was conducted from January 2010 to December 2010 to determine the optimal time for discontinuing continuous renal replacement therapy (CRRT) by evaluating factors predictive of successful discontinuation in patients with acute kidney injury. Analysis was performed for patients after CRRT was discontinued because of renal function recovery. Patients were divided into two groups according to the success or failure of CRRT discontinuation. In multivariate logistic regression analysis, urine output at discontinuation, creatinine level and CRRT duration were found to be significant variables (area under the receiver operating characteristic curve for urine output, 0.814). In conclusion, we found that higher urine output, lower creatinine and shorter CRRT duration were significant factors to predict successful discontinuation of CRRT.

引用

页码：453 / 457

页数：5

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