Allylmalonate as an Activator Subunit for the Initiation of Relay Ring-Closing Metathesis Reactions

被引：8

作者：

Hoye, Thomas R. ^{[1
]}

Jeon, Junha ^{[1
]}

Tennakoon, Manomi A. ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 09期

基金：

美国国家卫生研究院;

关键词：

cyclization; metathesis; reaction mechanisms; ruthenium; CATALYSTS; EFFICIENT; INSIGHTS; STRATEGY; ANALOG;

D O I：

10.1002/anie.201005044

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Passing the baton: The relay ring-closing metathesis (RRCM) reaction of complex polyenes 1 has been studied. Several relay subunits (T) were examined and many did not sufficiently activate the RRCM. An allylmalonate-containing relay subunit solved this problem, and efficiently lead to the diene 2. TIPS=triisopropylsilyl. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2141 / 2143

页数：3

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