Association between D-dimer levels and post-acute sequelae of SARS-CoV-2 in patients from a tertiary care center

被引:13
作者
Kalaivani, M. K. [1 ]
Dinakar, Shanthi [2 ]
机构
[1] Sree Balaji Med Coll & Hosp, Res Ctr Cellular Genom & Canc Res, Chennai 600044, Tamil Nadu, India
[2] Sree Balaji Med Coll & Hosp, Dept Biochem, Chennai 600044, Tamil Nadu, India
关键词
biomarker; COVID-19; D-dimer; PASC; post-acute sequelae of SARS-CoV-2;
D O I
10.2217/bmm-2022-0050
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Post-acute sequelae of SARS-CoV-2 (PASC) is becoming an important concern in SARS-CoV-infected people. The pathophysiology behind PASC is unknown, and much study should be carried out to check the D-dimer levels in the PASC population. Methodology: In COVID-19 patients, the D-dimer level was checked during admission and discharge, and a follow-up study was carried out after 3 and 6 months of discharge. The results were compared with the appropriate statistical tests. Results: Patients had a high D-dimer value than the normal range, and the elevated D-dimer value continued to increase up to 6 months. Conclusion: Persistence of PASC has a direct correlation with increased D-dimer values. D-dimer can be used as biomarker in PASC patients.
引用
收藏
页码:833 / 838
页数:6
相关论文
共 18 条
  • [1] D-dimer antigen: current concepts and future prospects
    Adam, Soheir S.
    Key, Nigel S.
    Greenberg, Charles S.
    [J]. BLOOD, 2009, 113 (13) : 2878 - 2887
  • [2] Implications of the second wave of COVID-19 in India
    Asrani, Purva
    Eapen, Mathew Suji
    Hassan, Md Imtaiyaz
    Sohal, Sukhwinder Singh
    [J]. LANCET RESPIRATORY MEDICINE, 2021, 9 (09) : E91 - E92
  • [3] Persistent Symptoms in Patients After Acute COVID-19
    Carfi, Angelo
    Bernabei, Roberto
    Landi, Francesco
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (06): : 603 - 605
  • [4] Management of post-acute covid-19 in primary care
    Greenhalgh, Trisha
    Knight, Matthew
    A'Court, Christine
    Buxton, Maria
    Husain, Laiba
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2020, 370
  • [5] The poor prognosis and influencing factors of high D-dimer levels for COVID-19 patients
    He, Xiaokang
    Yao, Fei
    Chen, Jie
    Wang, Yan
    Fang, Xiangming
    Lin, Xuan
    Long, Hui
    Wang, Qiang
    Wu, Qingming
    [J]. SCIENTIFIC REPORTS, 2021, 11 (01)
  • [6] Huang CL, 2021, LANCET, V397, P220, DOI [10.1016/S0140-6736(20)32656-8, 10.1016/S0140-6736(23)00810-3]
  • [7] COVID-19 cytokine storm: the interplay between inflammation and coagulation
    Jose, Ricardo J.
    Manuel, Ari
    [J]. LANCET RESPIRATORY MEDICINE, 2020, 8 (06) : E46 - E47
  • [8] Impact of persistent D-dimer elevation following recovery from COVID-19
    Lehmann, Antje
    Prosch, Helmut
    Zehetmayer, Sonja
    Gysan, Maximilian Robert
    Bernitzky, Dominik
    Vonbank, Karin
    Idzko, Marco
    Gompelmann, Daniela
    [J]. PLOS ONE, 2021, 16 (10):
  • [9] Review of D-dimer testing: Good, Bad, and Ugly
    Linkins, L. -A.
    Lapner, S. Takach
    [J]. INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2017, 39 : 98 - 103
  • [10] Lisa BK., COVID 19 VTE ANTICOA