Intracellular effects of okadaic acid in the blue mussel Mytilus edulis, and rainbow trout Oncorhynchus mykiss

被引：23

作者：

Svensson, S ^{[1
]}

Forlin, L ^{[1
]}

机构：

[1] Gothenburg Univ, Dept Zoophysiol, S-41390 Gothenburg, Sweden

来源：

MARINE ENVIRONMENTAL RESEARCH | 1998年 / 46卷 / 1-5期

关键词：

D O I：

10.1016/S0141-1136(97)00099-8

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The effects of okadaic acid (OA) on protein phosphatase (PP) and glycogen synthase (GS) activity was investigated in the blue mussel and rainbow trout. In both species, PP activity was inhibited by 200 nM inhibitor-2 (I-2) as well as 2 nM OA indicating the presence of both type I and type 2A phosphatases. GS activity was measured in an in vitro tissue slice method. Ten mu M Od inhibited GS activity in rainbow trout but did not alter GS activity hz the blue mussel. Also, feeding the mussels the OA-producing algae Prorocentrum lima had no effect on GS. These results seem to indicate that there nth be protective mechanisms against harmful effects of OA in the blue mussel. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：449 / 452

页数：4

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