DESIGN, SYNTHESIS AND CHARACTERIZATION OF SMALL MOLECULE GROUP II METABOTROPIC GLUTAMATE RECEPTOR ALLOSTERIC MODULATORS

被引:0
|
作者
Cosford, N. D. P. [1 ]
机构
[1] Sanford Burnham Prebys Med Discovery Inst, La Jolla, CA USA
关键词
RATS;
D O I
暂无
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
292
引用
收藏
页码:129A / 129A
页数:1
相关论文
共 50 条
  • [1] Design, synthesis, and preclinical characterization of small molecule group II metabotropic glutamate receptor positive allosteric modulators
    Cosford, Nicholas
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [2] Recent Progress in the Synthesis and Characterization of Group II Metabotropic Glutamate Receptor Allosteric Modulators
    Sheffler, Douglas J.
    Pinkerton, Anthony B.
    Dahl, Russell
    Markou, Athina
    Cosford, Nicholas D. P.
    ACS CHEMICAL NEUROSCIENCE, 2011, 2 (08): : 382 - 393
  • [3] Group II metabotropic glutamate receptors (mGluRs): Design and synthesis of small molecule modulators
    Cosford, Nicholas D. P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [4] Design and synthesis of novel metabotropic glutamate receptor allosteric modulators
    Stankiewicz, Anna
    Bugno, Ryszard
    Branski, Piotr
    Bojarski, Andrzej J.
    PHARMACOLOGICAL REPORTS, 2012, 64 (02) : 473 - 474
  • [5] Design and synthesis of novel metabotropic glutamate receptor allosteric modulators
    Anna Stankiewicz
    Ryszard Bugno
    Piotr Brański
    Andrzej J. Bojarski
    Pharmacological Reports, 2012, 64 : 473 - 474
  • [6] Design, synthesis and evaluation of Novel Group II Metabotropic Glutamate Receptor Allosteric Modulators in rodent models of CNS disorders
    Cosford, N. D. P.
    Dhanya, R.
    Sidique, S.
    Dahl, R.
    D'Souza, M. S.
    Semenova, S.
    Der-Avakian, A.
    Conn, P. J.
    Sheffler, D. J.
    Markou, A.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2014, 17 : 9 - 9
  • [7] Group I and group II metabotropic glutamate receptor allosteric modulators as novel potential antipsychotics
    Walker, Adam G.
    Conn, P. Jeffrey
    CURRENT OPINION IN PHARMACOLOGY, 2015, 20 : 40 - 45
  • [8] Synthesis and Optimization of Small Molecule Negative Allosteric Modulators (NAMs) of Group II Metabotropic Glutamate Receptors (mGlus) for the Treatment of Mental Disorders
    Dhanya, R. P.
    Sheffler, D. J.
    Herath, A.
    Davis, M.
    Lee, P. S.
    Yang, L.
    Nickols, H. H.
    Cho, H. P.
    Conn, P. J.
    Der-Avakian, A.
    Markou, A.
    Cosford, N. D. P.
    CURRENT NEUROPHARMACOLOGY, 2014, 12 : 14 - 14
  • [9] Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia
    Fell, Matthew J.
    McKinzie, David L.
    Monn, James A.
    Svensson, Kjell A.
    NEUROPHARMACOLOGY, 2012, 62 (03) : 1473 - 1483
  • [10] Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators
    Fernandez-Duenas, Victor
    Qian, Mingcheng
    Argerich, Josep
    Amaral, Carolina
    Risseeuw, Martijn D. P.
    Van Calenbergh, Serge
    Ciruela, Francisco
    MOLECULES, 2020, 25 (07):