Conjugate reduction of α,β-unsaturated carbonyl compounds.: Selective inhibition of benzyl ether hydrogenolysis by NH4OH/MeOH

被引：6

作者：

Dias, LC ^{[1
]}

Campano, PL ^{[1
]}

机构：

[1] Univ Estadual Campinas, Inst Quim, BR-13083970 Campinas, SP, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 1998年 / 9卷 / 01期

关键词：

conjugate reduction; inhibition of benzyl ether hydrogenolysis; chemoselective reduction of alpha; beta-unsaturated compounds; selective catalytic hydrogenation;

D O I：

10.1590/S0103-50531998000100017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of alpha,beta-unsaturated alkyl and aryl ketones, esters and N-methoxy-N-methyl-amides (Weinreb amides) containing an O-benzyl protecting group undergo conjugate reduction by H-2/Pd/C in the presence of 2N NH4OH/MeOH at room temperature and ordinary pressure leaving the benzyl group intact.

引用

页码：97 / 99

页数：3

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