Efficient one-pot synthesis of propargylamines using zinc dust

被引：75

作者：

Kantam, M. Lakshmi ^{[1
]}

Balasubrahmanyam, V. ^{[1
]}

Kumar, K. B. Shiva ^{[1
]}

Venkanna, G. T. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Inorgan & Phys Chem Div, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 41期

关键词：

Zn dust; propargylamines; heterogeneous catalyst;

D O I：

10.1016/j.tetlet.2007.08.020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The one-pot synthesis of propargylamines is achieved efficiently via a three component coupling of various aldehydes, alkynes and amines using zinc dust under mild reaction conditions and in the absence of a co-catalyst. Zinc dust was recovered quantitatively by simple centrifugation and reused. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：7332 / 7334

页数：3

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