COVID-19 during Early Phase of Autologous Stem Cell Transplantation

被引：2

作者：

Milczarek, Slawomir ^{[1
,2
]}

Baumert, Bartlomiej ^{[1
,2
]}

Sobus, Anna ^{[1
]}

Wilk-Milczarek, Ewa ^{[3
]}

Sommerfeld, Krzysztof ^{[2
]}

Osekowska, Bogumila ^{[2
]}

Borowiecka, Ewa ^{[2
]}

Paczkowska, Edyta ^{[1
,2
]}

Lanocha, Aleksandra ^{[2
]}

Poncyliusz, Wojciech ^{[4
]}

Jarosz, Konrad ^{[5
]}

Machalinski, Boguslaw ^{[1
,2
]}

机构：

[1] Pomeranian Med Univ, Dept Gen Pathol, PL-70111 Szczecin, Poland

[2] Pomeranian Med Univ, Dept Hematol & Transplantol, PL-71252 Szczecin, Poland

[3] Pomeranian Med Univ, Dept Gen & Dent Radiol, PL-70111 Szczecin, Poland

[4] Pomeranian Med Univ, Dept Diagnost Imaging & Intervent Radiol, PL-71252 Szczecin, Poland

[5] Pomeranian Med Univ, Dept Anaesthesiol & Intens Care, PL-71252 Szczecin, Poland

来源：

MEDICINA-LITHUANIA | 2021年 / 57卷 / 07期

关键词：

COVID-19; AHSCT; lymphoblastic lymphoma; chemotherapy; CLINICAL CHARACTERISTICS;

D O I：

10.3390/medicina57070724

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient's rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our report emphasizes the need to investigate whether timely steroid therapy upon neutrophil engraftment in the setting of COVID-19 could limit the extent of lung injury and prevent ARDS. Furthermore, we discuss a significant issue of possible prolonged incubation of the virus in heavily pretreated hematological patients.

引用

页数：5

共 14 条

[1] COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps
Borges, Leandro
Pithon-Curi, Tania Cristina
Curi, Rui
Hatanaka, Elaine
[J]. MEDIATORS OF INFLAMMATION, 2020, 2020
[2] ElGohary Ghada M, 2022, Hematol Oncol Stem Cell Ther, V15, P45, DOI 10.1016/j.hemonc.2020.07.005
[3] Remdesivir for 5 or 10 Days in Patients with Severe Covid-19
Goldman, Jason D.
Lye, David C. B.
Hui, David S.
Marks, Kristen M.
Bruno, Raffaele
Montejano, Rocio
Spinner, Christoph D.
Galli, Massimo
Ahn, Mi-Young
Nahass, Ronald G.
Chen, Yao-Shen
SenGupta, Devi
Hyland, Robert H.
Osinusi, Anu O.
Cao, Huyen
Blair, Christiana
Wei, Xuelian
Gaggar, Anuj
Brainard, Diana M.
Towner, William J.
Munoz, Jose
Mullane, Kathleen M.
Marty, Francisco M.
Tashima, Karen T.
Diaz, George
Subramanian, Aruna
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (19) : 1827 - 1837
[4] Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis
Hasan, Syed Shahzad
Capstick, Toby
Ahmed, Raees
Kow, Chia Siang
Mazhar, Faizan
Merchant, Hamid A.
Zaidi, Syed Tabish Razi
[J]. EXPERT REVIEW OF RESPIRATORY MEDICINE, 2020, 14 (11) : 1149 - 1163
[5] Horby P, 2021, NEW ENGL J MED, V384, P693, DOI [10.1056/NEJMoa2021436, 10.1056/NEJMoa2022926]
[6] COVID-19 in bone marrow transplant recipients: reflecting on a single centre experience
Kanellopoulos, Alexandros
Ahmed, Maria Z.
Kishore, Bhuvan
Lovell, Richard
Horgan, Claire
Paneesha, Shankara
Lloyd, Rebecca
Salhan, Beena
Giles, Hannah
Chauhan, Saleena
Venkatadasari, Indrani
Khakwani, Muhammad
Murthy, Vidhya
Xenou, Evgenia
Dassanayake, Hansini
Srinath, Swathy
Kaparou, Maria
Nikolousis, Emmanouil
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2020, 190 (02) : E67 - E70
[7] The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
Ljungman, Per
Mikulska, Malgorzata
de la Camara, Rafael
Basak, Grzegorz W.
Chabannon, Christian
Corbacioglu, Selim
Duarte, Rafael
Dolstra, Harry
Lankester, Arjan C.
Mohty, Mohamad
Montoto, Silvia
Murray, John
de Latour, Regis Peffault
Snowden, John A.
Yakoub-Agha, Ibrahim
Verhouven, Bregje
Kroeger, Nicolaus
Styczynski, Jan
[J]. BONE MARROW TRANSPLANTATION, 2020, 55 (11) : 2071 - 2076
[8] Engraftment syndrome following autologous hematopoietic stem cell transplantation: definition of diagnostic criteria
Maiolino, A
Biasoli, I
Lima, J
Portugal, AC
Pulcheri, W
Nucci, M
[J]. BONE MARROW TRANSPLANTATION, 2003, 31 (05) : 393 - 397
[9] Passamonti F., 2020, study Lancet Haematol., V7, P745, DOI [10.1016/S2352-3026, DOI 10.1016/S2352-3026]
[10] Clinical characteristics and outcomes of COVID-19 in haematopoietic stem-cell transplantation recipients: an observational cohort study
Sharma, Akshay
Bhatt, Neel S.
St Martin, Andrew
Abid, Muhammad Bilal
Bloomquist, Jenni
Chemaly, Roy F.
Dandoy, Christopher
Gauthier, Jordan
Gowda, Lohith
Perales, Miguel-Angel
Seropian, Stuart
Shaw, Bronwen E.
Tuschl, Eileen E.
Zeidan, Amer M.
Riches, Marcie L.
Shah, Gunjan L.
[J]. LANCET HAEMATOLOGY, 2021, 8 (03): : E185 - E193

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