Paraoxonase-1 in female infertility: a possible role against oxidative stress-induced inflammation

被引：15
作者：
Marsillach, Judit [1 ]
Angel Checa, Miguel [2 ,3 ]
Pedro-Botet, Juan [2 ,3 ]
Carreras, Ramon [2 ,3 ]
Joven, Jorge [1 ]
Camps, Jordi [1 ]
机构：
[1] Hosp Univ St Joan, Ctr Recerca Biomed, Inst Invest Sanitaria Pere Virgili, Reus 43201, Catalunya, Spain
[2] Hosp del Mar, Dept Gynecol, Barcelona, Spain
[3] Hosp del Mar, Dept Internal Med, Barcelona, Spain
来源：
FERTILITY AND STERILITY | 2010年 / 94卷 / 03期
关键词：
Female infertility; inflammation; monocyte chemoattractant protein-1; oxidative stress; paraoxonase-1; LIFE-STYLE; HDL; IMPACT; PON1;
D O I：
10.1016/j.fertnstert.2009.11.043
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
In this observational, case-control study in infertile women, we observed elevated serum oxidative stress that was significantly correlated with an increase in serum paraoxonase-1 activity and without any evidence of a proinflammatory reaction. These results suggest a protective role of paraoxonase-1 against inflammation in this clinical setting. (Fertil Steril (R) 2010;94:1132-4. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码：1132 / 1134
页数：3
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