Elephant-to-Human Transmission of Tuberculosis, 2009

被引：52

作者：

Murphree, Rendi ^{[1
,2
]}

Warkentin, Jon V. ^{[1
]}

Dunn, John R. ^{[1
]}

Schaffner, William ^{[3
]}

Jones, Timothy F. ^{[1
,3
]}

机构：

[1] Tennessee Dept Hlth, Nashville, TN 37243 USA

[2] Ctr Dis Control & Prevent, Atlanta, GA USA

[3] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA

来源：

EMERGING INFECTIOUS DISEASES | 2011年 / 17卷 / 03期

关键词：

MYCOBACTERIUM-TUBERCULOSIS; INFECTION; DIAGNOSIS;

D O I：

10.3201/eid1703.101668

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2009, the Tennessee Department of Health received reports of 5 tuberculin skin test (TST) conversions among employees of an elephant refuge and isolation of Mycobacterium tuberculosis from a resident elephant. To determine the extent of the outbreak and identify risk factors for TST conversion, we conducted a cohort study and onsite assessment. Risk for conversion was increased for elephant caregivers and administrative employees working in the barn housing the M. tuberculosis-infected elephant or in offices connected to the barn (risk ratio 20.3, 95% confidence interval 2.8-146.7). Indirect exposure to aerosolized M. tuberculosis and delayed or inadequate infection control practices likely contributed to transmission. The following factors are needed to reduce risk for M. tuberculosis transmission in the captive elephant industry: increased knowledge about M. tuberculosis infection in elephants, improved infection control practices, and specific occupational health programs.

引用

页码：366 / 371

页数：6

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