Magnetic Resonance Cancer Nanotheranostics

被引：2

作者：

Orel, V. E. ^{[1
,2
]}

Tselepi, M. ^{[3
,8
]}

Mitrelias, T. ^{[3
]}

Shevchenko, A. D. ^{[4
]}

Rykhalskiy, O. Y. ^{[1
,2
]}

Golovko, T. S. ^{[5
]}

Ganich, O. V. ^{[5
]}

Romanov, A. V. ^{[1
]}

Orel, V. B. ^{[6
]}

Burlaka, A. P. ^{[7
]}

Lukin, S. N. ^{[7
]}

Barnes, C. H. W. ^{[3
]}

机构：

[1] Natl Canc Inst, Med Phys & Bioengn Res Lab, Kiev, Ukraine

[2] Igor Sikorsky Kyiv Polytech Inst, Dept Biomed Engn, Kiev, Ukraine

[3] Univ Cambridge, Cavendish Lab, JJ Thomson Ave, Cambridge, England

[4] GV Kurdyumov Inst Met Phys, Kiev, Ukraine

[5] Natl Canc Inst, Res Dept Radiodiagnost, Kiev, Ukraine

[6] Bogomolets Natl Med Univ, Kiev, Ukraine

[7] NAS Ukraine, RE Kavetsky Inst Expt Pathol Oncol & Radiobiol, Kiev, Ukraine

[8] Univ Ioannina, Dept Phys, Ioannina, Greece

来源：

WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2018, VOL 3 | 2019年 / 68卷 / 03期

关键词：

Magnetic resonance; Magnetic nanocomplex; Doxorubicin; Tumor;

D O I：

10.1007/978-981-10-9023-3_120

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

It is well known that the magnetic spin effects during nanotherapy can cause tumor cell apoptosis and necrosis based on redox reactions. The current study was carried out on C57Bl/6 mice with Lewis lung carcinoma. The magnetic nanocomplex administration combined with the impact of magnetic resonance system (1.5 T) showed maximal antitumor and antimetastatic effects. The electron spin resonance spectra have been used as diagnostic markers and recorded a change in the tumor redox state based on chemical species such as NO-FeS-proteins and ubisemiquinone. The technology of magnetic resonance nanotheranostics could potentially allow to improve the antitumor effect of chemotherapeutic agents in disseminated cancer therapy.

引用

页码：651 / 654

页数：4

共 50 条

[41] Seeing Better and Going Deeper in Cancer Nanotheranostics
Sivasubramanian, Maharajan
Chuang, Yao Chen
Chen, Nai-Tzu
Lo, Leu-Wei
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (14)
[42] Gadolinium-Chelated Conjugated Polymer-Based Nanotheranostics for Photoacoustic/Magnetic Resonance/NIR-II Fluorescence Imaging-Guided Cancer Photothermal Therapy
Hu, Xiaoming
Tang, Yufu
Hu, Yuxuan
Lu, Feng
Lu, Xiaomei
Wang, Yuqi
Li, Jie
Li, Yuanyuan
Ji, Yu
Wang, Wenjun
Ye, Deju
Fan, Quli
Huang, Wei
THERANOSTICS, 2019, 9 (14): : 4168 - 4181
[43] Use of macrophage as a Trojan horse for cancer nanotheranostics
Qi, Yu
Yan, Xu
Xia, Tian
Liu, Sijin
MATERIALS & DESIGN, 2021, 198
[44] Magnetic Resonance Imaging of Rectal Cancer
Dewhurst, Catherine E.
Mortele, Koenraad J.
RADIOLOGIC CLINICS OF NORTH AMERICA, 2013, 51 (01) : 121 - +
[45] Magnetic resonance imaging and prostate cancer
Cornud, F.
Villers, A.
Mongiat-Artus, P.
Rebillard, X.
Soulie, M.
PROGRES EN UROLOGIE, 2008, 18 (10): : 621 - 633
[46] Magnetic Resonance Imaging for Lung Cancer
Koyama, Hisanobu
Ohno, Yoshiharu
Seki, Shinichiro
Nishio, Mizuho
Yoshikawa, Takeshi
Matsumoto, Sumiaki
Sugimura, Kazuro
JOURNAL OF THORACIC IMAGING, 2013, 28 (03) : 138 - 150
[47] Magnetic resonance imaging of colorectal cancer
Zagoria, RJ
Wolfman, NT
SEMINARS IN ROENTGENOLOGY, 1996, 31 (02) : 162 - 165
[48] Nanoplatforms for magnetic resonance imaging of cancer
Cywinska, Monika A.
Grudzinski, Ireneusz P.
Cieszanowski, Andrzej
Bystrzejewski, Michal
Poplawska, Magdalena
POLISH JOURNAL OF RADIOLOGY, 2011, 76 (02) : 28 - 36
[49] Magnetic resonance imaging in prostate cancer
S D Heenan
Prostate Cancer and Prostatic Diseases, 2004, 7 : 282 - 288
[50] Magnetic resonance imaging of prostate cancer
Guneyli, Serkan
Erdem, Cemile Zuhal
Erdem, Lutfi Oktay
CLINICAL IMAGING, 2016, 40 (04) : 601 - 609

← 1 2 3 4 5 →