Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques

被引：11

作者：

Li Lin

Wang JianNong

Ren JianXun

Xiang JunFeng

Tang Yalin ^{[1
]}

Liu JianXun

Han Ding

机构：

[1] Chinese Acad Sci, Inst Chem, State Key Lab Strcut Chem Unstable & Stable Speci, Beijing 100080, Peoples R China

[2] China Acad Chinese Med Sci, Xi Yuan Hosp, Beijing 100091, Peoples R China

来源：

CHINESE SCIENCE BULLETIN | 2007年 / 52卷 / 22期

关键词：

metabonomics; NMR; Qi deficiency and blood stasis syndrome; urine;

D O I：

10.1007/s11434-007-0389-4

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate, creatinine, 2-oxoglutarate (2-OG), citrate, taurine, trimethylamine-N-oxide(TMAO), succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi deficiency and blood stasis syndrome.

引用

收藏

页码：3068 / 3073

页数：6

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