Live-cell-permeable poly (p-phenylene ethynylene)

被引:152
|
作者
Moon, Joong Ho [1 ]
McDaniel, William [1 ]
MacLean, Paul [1 ]
Hancock, Lawrence E. [1 ]
机构
[1] ICx Technologies, Cambridge, MA 02142 USA
关键词
D O I
10.1002/anie.200701991
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Light up my life: Stable, bright, conjugated-polymer nanoparticles (CPNs) show promise for fluorescence imaging of live cells. The cell-permeable CPNs are synthesized by a simple solvent exchange, and accumulate exclusively in the cytosol (see picture) without any noticeable inhibition of cell viability. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:8223 / 8225
页数:3
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