High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers

被引:66
作者
Ahn, Joongho
Kim, Jin Young
Choi, Wonseok
Kim, Chulhong [1 ]
机构
[1] Pohang Univ Sci & Technol, Dept Elect Engn, Pohang 37673, South Korea
来源
PHOTOACOUSTICS | 2021年 / 23卷
基金
新加坡国家研究基金会;
关键词
Photoacoustic microscopy; Blood vessel; Hemodynamics; Pulsation; Perfusion; Oxygen saturation; Digital vasculature; REACTIVE HYPEREMIA; BLOOD-FLOW; TOMOGRAPHY; DOPPLER; ANGIOGRAPHY; OXYGENATION; ULTRASOUND; MICROSCOPY; PRINCIPLES;
D O I
10.1016/j.pacs.2021.100282
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Functional imaging of microvascular dynamics in extremities delivers intuitive information for early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high-speed photoacoustic microscopy (PAM) visualizes and measures multiparametric information of microvessel networks in vivo such as morphology, flow, oxygen saturation, and metabolic rate. Here, we demonstrate high-resolution photoacoustic monitoring of vascular dynamics in human fingers. We photoacoustically monitored the position displacement of blood vessels associated with arterial pulsation in human fingers. Then, during and after arterial occlusion, we photoacoustically quantified oxygen consumption and blood perfusion in the fingertips. The results demonstrate that high-resolution functional PAM could be a vital tool in peripheral vascular examination for measuring heart rate, oxygen consumption, and/or blood perfusion.
引用
收藏
页数:9
相关论文
共 71 条
[1]   Photoplethysmography for blood volumes and oxygenation changes during intermittent vascular occlusions [J].
Abay, T. Y. ;
Kyriacou, P. A. .
JOURNAL OF CLINICAL MONITORING AND COMPUTING, 2018, 32 (03) :447-455
[2]   Assessing nailfold microvascular structure with ultra-wideband raster-scan optoacoustic mesoscopy [J].
Aguirre, J. ;
Hindelang, B. ;
Berezhnoi, Andrei ;
Darsow, U. ;
Lauffer, F. ;
Eyerich, K. ;
Biedermann, T. ;
Ntziachristos, V. .
PHOTOACOUSTICS, 2018, 10 :31-37
[3]   A review of clinical photoacoustic imaging: Current and future trends [J].
Attia, Amalina Binte Ebrahim ;
Balasundaram, Ghayathri ;
Moothanchery, Mohesh ;
Dinish, U. S. ;
Bi, Renzhe ;
Ntziachristos, Vasilis ;
Olivo, Malini .
PHOTOACOUSTICS, 2019, 16
[4]   Super Wide-Field Photoacoustic Microscopy of Animals and Humans <italic>In Vivo</italic> [J].
Baik, Jin Woo ;
Kim, Jin Young ;
Cho, Seonghee ;
Choi, Seongwook ;
Kim, Jongbeom ;
Kim, Chulhong .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2020, 39 (04) :975-984
[5]   Microvascular Disease, Peripheral Artery Disease, and Amputation [J].
Beckman, Joshua A. ;
Duncan, Meredith S. ;
Damrauer, Scott M. ;
Wells, Quinn S. ;
Barnett, Joey V. ;
Wasserman, David H. ;
Bedimo, Roger J. ;
Butt, Adeel A. ;
Marconi, Vincent C. ;
Sico, Jason J. ;
Tindle, Hilary A. ;
Bonaca, Marc P. ;
Aday, Aaron W. ;
Freiberg, Matthew S. .
CIRCULATION, 2019, 140 (06) :449-458
[6]   In vivo label-free functional photoacoustic monitoring of ischemic reperfusion [J].
Bi, Renzhe ;
Dinish, U. S. ;
Goh, Chi Ching ;
Imai, Toru ;
Moothanchery, Mohesh ;
Li, Xiuting ;
Kim, Jin Young ;
Jeon, Seungwan ;
Pu, Yang ;
Kim, Chulhong ;
Ng, Lai Guan ;
Wang, Lihong V. ;
Olivo, Malini .
JOURNAL OF BIOPHOTONICS, 2019, 12 (07)
[7]  
Braaf B, 2019, High Resolution Imaging In Microscopy And Ophthalmology: New Frontiers In Biomedical Optics, P161
[8]  
Castaneda Denisse, 2018, Int J Biosens Bioelectron, V4, P195, DOI 10.15406/ijbsbe.2018.04.00125
[9]   Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate [J].
Chen, Jiangbo ;
Zhang, Yachao ;
He, Linyun ;
Liang, Yizhi ;
Wang, Lidai .
PHOTOACOUSTICS, 2020, 20 (20)
[10]   3D PHOVIS: 3D photoacoustic visualization studio [J].
Cho, Seonghee ;
Baik, Jinwoo ;
Managuli, Ravi ;
Kim, Chulhong .
PHOTOACOUSTICS, 2020, 18