共 153 条
Aspirin resistance: Effect of clinical, biochemical and genetic factors
被引:93
作者:

FitzGerald, Richard
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Liverpool, Wolfson Ctr Personalised Med, Dept Pharmacol, Liverpool L69 3GL, Merseyside, England Univ Liverpool, Wolfson Ctr Personalised Med, Dept Pharmacol, Liverpool L69 3GL, Merseyside, England

Pirmohamed, Munir
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Liverpool, Wolfson Ctr Personalised Med, Dept Pharmacol, Liverpool L69 3GL, Merseyside, England Univ Liverpool, Wolfson Ctr Personalised Med, Dept Pharmacol, Liverpool L69 3GL, Merseyside, England
机构:
[1] Univ Liverpool, Wolfson Ctr Personalised Med, Dept Pharmacol, Liverpool L69 3GL, Merseyside, England
基金:
英国惠康基金;
关键词:
Aspirin resistance;
Aspirin;
Cardiovascular disease;
Anti-platelets;
Platelet function testing;
Pharmacogenetics;
SOLUBLE CD40 LIGAND;
LOW-DOSE ASPIRIN;
PLATELET-FUNCTION TESTS;
VON-WILLEBRAND-FACTOR;
ACUTE CORONARY SYNDROME;
INSENSITIVE EICOSANOID BIOSYNTHESIS;
RECURRENT CARDIOVASCULAR EVENTS;
ATHEROSCLEROSIS RISK-FACTORS;
TRANSIENT ISCHEMIC ATTACK;
C-REACTIVE PROTEIN;
D O I:
10.1016/j.pharmthera.2011.01.011
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Aspirin is one of the cornerstones of treatment for cardiovascular disease. However, some patients may be 'resistant' to its effect: this is associated with adverse cardiovascular outcomes and increased mortality. Measuring response to aspirin is often difficult and there is no accepted definition of aspirin resistance. Many assays are available to test aspirin sensitivity but most are not specific to aspirin and the degree of agreement between different assays is poor. Each assay has its own advantages and disadvantages, and there is currently no one assay that can be recommended for routine clinical practise. There are also many potential modifiers of aspirin response including aspirin dose, non-compliance, disease severity, genetic factors, inflammation, diabetes mellitus, hyperlipidaemia, smoking and interacting drugs. Treating the underlying cause may improve aspirin sensitivity but current data are contradictory with no large clinical trials that have addressed this. Further work is required in this area to determine whether and how aspirin resistance is important clinically, what the best measurement is phenotypically and how this should be used in clinical practise, and whether there are any genetic predisposing factors. This will require well designed prospective studies which take into account the numerous confounding factors that can modify aspirin resistance. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:213 / 225
页数:13
相关论文
共 153 条
[31]
Lack of aspirin effect: Aspirin resistance or resistance to taking aspirin?
[J].
Cotter, G
;
Shemesh, E
;
Zehavi, M
;
Dinur, I
;
Rudnick, A
;
Milo, O
;
Vered, Z
;
Krakover, R
;
Kaluski, E
;
Kornberg, A
.
AMERICAN HEART JOURNAL,
2004, 147 (02)
:293-300

Cotter, G
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Shemesh, E
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Zehavi, M
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Dinur, I
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Rudnick, A
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Milo, O
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Vered, Z
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Krakover, R
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Kaluski, E
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA

Kornberg, A
论文数: 0 引用数: 0
h-index: 0
机构: Mt Sinai Med Ctr, Dept Psychiat, New York, NY 10029 USA
[32]
Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers
[J].
Cox, Dermot
;
Maree, Andrew O.
;
Dooley, Michelle
;
Conroy, Ronan
;
Byrne, Michael F.
;
Fitzgerald, Desmond J.
.
STROKE,
2006, 37 (08)
:2153-2158

Cox, Dermot
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland

Maree, Andrew O.
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland

Dooley, Michelle
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland

Conroy, Ronan
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland

Byrne, Michael F.
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland

Fitzgerald, Desmond J.
论文数: 0 引用数: 0
h-index: 0
机构: Royal Coll Surgeons Ireland, Dept Clin Pharmacol, Dublin 2, Ireland
[33]
Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100 - A systematic review
[J].
Crescente, Marilena
;
Di Castelnuovo, Augusto
;
Lacoviello, Licia
;
Vermylen, Jos
;
Cerletti, Chiara
;
de Gaetano, Giovanni
.
THROMBOSIS AND HAEMOSTASIS,
2008, 99 (01)
:14-26

Crescente, Marilena
论文数: 0 引用数: 0
h-index: 0
机构:
Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy

Di Castelnuovo, Augusto
论文数: 0 引用数: 0
h-index: 0
机构:
Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy

Lacoviello, Licia
论文数: 0 引用数: 0
h-index: 0
机构:
Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy

Vermylen, Jos
论文数: 0 引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Ctr Mol & Vasc Biol, Louvain, Belgium Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy

Cerletti, Chiara
论文数: 0 引用数: 0
h-index: 0
机构:
Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy

de Gaetano, Giovanni
论文数: 0 引用数: 0
h-index: 0
机构:
Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy Catholic Univ, John Paul Ctr High Technol Res & Educ Biomed Sci, Res Labs, I-86100 Campobasso, Italy
[34]
Associations between soluble CD40 ligand, atherosclerosis risk factors, and subclinical atherosclerosis -: Results from the Dallas Heart Study
[J].
de Lemos, JA
;
Zirlik, A
;
Schönbeck, U
;
Varo, N
;
Murphy, SA
;
Khera, A
;
McGuire, DK
;
Stanek, G
;
Lo, HS
;
Nuzzo, R
;
Morrow, DA
;
Peshock, R
;
Libby, P
.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,
2005, 25 (10)
:2192-2196

de Lemos, JA
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Zirlik, A
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Schönbeck, U
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Varo, N
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Murphy, SA
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Khera, A
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

McGuire, DK
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Stanek, G
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Lo, HS
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Nuzzo, R
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Morrow, DA
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Peshock, R
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

Libby, P
论文数: 0 引用数: 0
h-index: 0
机构: Univ Texas, SW Med Ctr, Div Cardiol, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA
[35]
The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients - An analysis from the aspirin-induced platelet effect (ASPECT) study
[J].
DiChiara, Joseph
;
Bliden, Kevin P.
;
Tantry, Udaya S.
;
Hamed, Miruais S.
;
Antonino, Mark J.
;
Suarez, Thomas A.
;
Bailon, Oscar
;
Singla, Anand
;
Gurbel, Paul A.
.
DIABETES,
2007, 56 (12)
:3014-3019

DiChiara, Joseph
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Bliden, Kevin P.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Tantry, Udaya S.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Hamed, Miruais S.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Antonino, Mark J.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Suarez, Thomas A.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Bailon, Oscar
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Singla, Anand
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Gurbel, Paul A.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
[36]
Platelet function measured by VerifyNow™ identifies generalized high platelet reactivity in aspirin treated patients
[J].
Dichiara, Joseph
;
Bliden, Kevin P.
;
Tantry, Udaya S.
;
Chaganti, Srivasavi K.
;
Kreutz, Rolf P.
;
Gesheff, Tania B.
;
Kreutz, Yvonne
;
Gurbel, Paul A.
.
PLATELETS,
2007, 18 (06)
:414-423

Dichiara, Joseph
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Bliden, Kevin P.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Tantry, Udaya S.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Chaganti, Srivasavi K.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Kreutz, Rolf P.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Gesheff, Tania B.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Kreutz, Yvonne
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA

Gurbel, Paul A.
论文数: 0 引用数: 0
h-index: 0
机构:
Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA Sinai Ctr Thrombosis Res, Baltimore, MD 21215 USA
[37]
What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke?
[J].
Dippel, DWJ
;
van Kooten, F
;
Leebeek, FWG
;
van Vliet, HHDM
;
Mehicevic, A
;
Li, SSC
;
Koudstaal, PJ
.
CEREBROVASCULAR DISEASES,
2004, 17 (04)
:296-302

Dippel, DWJ
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

van Kooten, F
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

Leebeek, FWG
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

van Vliet, HHDM
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

Mehicevic, A
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

Li, SSC
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands

Koudstaal, PJ
论文数: 0 引用数: 0
h-index: 0
机构: Erasmus Med Ctr, Dept Neurol, NL-3000 CA Rotterdam, Netherlands
[38]
Incomplete Inhibition of Thromboxane Biosynthesis by Acetylsalicylic Acid Determinants and Effect on Cardiovascular Risk
[J].
Eikelboom, John W.
;
Hankey, Graeme J.
;
Thom, Jim
;
Bhatt, Deepak L.
;
Steg, P. Gabriel
;
Montalescot, Gilles
;
Johnston, S. Claiborne
;
Steinhubl, Steven R.
;
Mak, Koon-Hou
;
Easton, J. Donald
;
Hamm, Christian
;
Hu, Tingfei
;
Fox, Keith A. A.
;
Topol, Eric J.
.
CIRCULATION,
2008, 118 (17)
:1705-1712

Eikelboom, John W.
论文数: 0 引用数: 0
h-index: 0
机构:
McMaster Univ, Hamilton, ON, Canada Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Hankey, Graeme J.
论文数: 0 引用数: 0
h-index: 0
机构:
Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Thom, Jim
论文数: 0 引用数: 0
h-index: 0
机构:
Royal Perth Hosp, Dept Haematol, Perth, WA 6000, Australia Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Bhatt, Deepak L.
论文数: 0 引用数: 0
h-index: 0
机构:
VA Boston Healthcare Syst, Boston, MA USA
Brigham & Womens Hosp, Boston, MA 02115 USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Steg, P. Gabriel
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Paris 07, INSERM, AP HP, U698, Paris, France Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Montalescot, Gilles
论文数: 0 引用数: 0
h-index: 0
机构:
Hop La Pitie Salpetriere, Inst Cardiol, APHP, Paris, France
Hop La Pitie Salpetriere, INSERM, U856, Paris, France Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Johnston, S. Claiborne
论文数: 0 引用数: 0
h-index: 0
机构:
UCSF Neurol, San Francisco, CA USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Steinhubl, Steven R.
论文数: 0 引用数: 0
h-index: 0
机构:
Weis Ctr Res, Geisinger Clin, Danville, PA 17822 USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Mak, Koon-Hou
论文数: 0 引用数: 0
h-index: 0
机构:
Gleneagles Med Ctr, Singapore, Singapore Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Easton, J. Donald
论文数: 0 引用数: 0
h-index: 0
机构:
Brown Univ, Providence, RI 02912 USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Hamm, Christian
论文数: 0 引用数: 0
h-index: 0
机构:
Kerckhoff Heart Ctr, Bad Nauheim, Germany Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Hu, Tingfei
论文数: 0 引用数: 0
h-index: 0
机构:
Cleveland Clin, Cleveland, OH 44106 USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Fox, Keith A. A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Edinburgh, Edinburgh, Midlothian, Scotland
Royal Infirm Edinburgh NHS Trust, Edinburgh, Midlothian, Scotland Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia

Topol, Eric J.
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, La Jolla, CA 92037 USA
Scripps Clin, La Jolla, CA 92037 USA Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA 6000, Australia
[39]
Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial
[J].
Eikelboom, JW
;
Hankey, GJ
;
Thom, J
;
Claxton, A
;
Yi, Q
;
Gilmore, G
;
Staton, J
;
Barden, A
;
Norman, PE
.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS,
2005, 3 (12)
:2649-2655

Eikelboom, JW
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Hankey, GJ
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Thom, J
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Claxton, A
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Yi, Q
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Gilmore, G
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Staton, J
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Barden, A
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada

Norman, PE
论文数: 0 引用数: 0
h-index: 0
机构: McMaster Univ, Dept Med, HGH McMaster Clin, Hamilton, ON L8L 2X2, Canada
[40]
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
[J].
Eikelboom, JW
;
Hirsh, J
;
Weitz, JI
;
Johnston, M
;
Yi, Q
;
Yusuf, S
.
CIRCULATION,
2002, 105 (14)
:1650-1655

Eikelboom, JW
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia

Hirsh, J
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia

Weitz, JI
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia

Johnston, M
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia

Yi, Q
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia

Yusuf, S
论文数: 0 引用数: 0
h-index: 0
机构: Univ Western Australia, Royal Perth Hosp, Thrombosis & Haemophila Unit, Dept Med, Perth, WA 6897, Australia