Determination of the susceptibility to different antimicrobial agents in Neisseria gonorrhoeae: A comparison of two methods

被引:0
作者
Pajaro, MC [1 ]
Barberis, IL [1 ]
机构
[1] Univ Nacl Rio Cuarto, Dept Microbiol & Inmunol, RA-5800 Rio Cuarto, Cordoba, Argentina
来源
ACTA BIOQUIMICA CLINICA LATINOAMERICANA | 1998年 / 32卷 / 02期
关键词
Neisseria gonorrhoeae; susceptibility; antimicrobial;
D O I
暂无
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Fifty strains of N. gonorrhoeae were isolated from women and men samples of genital tract received from the laboratory in Hospital of Rio Cuarto and private laboratory. The susceptibility to 5 antimicrobial was obtained by two methods: agar dilation and E-test (PDM epsilometer test). MICs (minimum inhibitory concentrations) obtained by the E-test was slightly lower than the one obtained by the classic method. A significant relationship (P < 0.001) between both methods was observed. The data obtained in the present study suggest that the E-test is an accurate alternative method on dilution agar and is a more appropriate technique for MIC determination, on the MICs of various antimicrobial agents for N. gonorrhoeae.
引用
收藏
页码:253 / 256
页数:4
相关论文
共 10 条
[1]  
FAMIGLIETTI A, 1997, 1 C INT INF MICR CLI, P337
[2]   COMPARISON OF CIPROFLOXACIN AND CEFTRIAXONE AS SINGLE-DOSE THERAPY FOR UNCOMPLICATED GONORRHEA IN WOMEN [J].
HOOK, EW ;
JONES, RB ;
MARTIN, DH ;
BOLAN, GA ;
MROCZKOWSKI, TF ;
NEUMANN, TM ;
HAAG, JJ ;
ECHOLS, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (08) :1670-1673
[3]  
JOYCE LF, 1992, J CLIN MICROBIOL, V29, P109
[4]   EMERGING IN-VITRO RESISTANCE TO QUINOLONES IN PENICILLINASE-PRODUCING NEISSERIA-GONORRHOEAE STRAINS IN HAWAII [J].
KNAPP, JS ;
OHYE, R ;
NEAL, SW ;
PAREKH, MC ;
HIGA, H ;
RICE, RJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (09) :2200-2203
[5]  
MENES MR, 1997, 1 C INT INF MICR CLI, pP268
[6]  
PRINS M, 1994, GENITOURIN MED, V70, P247
[7]   Cloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitidis [J].
Ropp, PA ;
Nicholas, RA .
JOURNAL OF BACTERIOLOGY, 1997, 179 (08) :2783-2787
[8]   DIVERSITY OF ISOLATES OF PENICILLINASE-PRODUCING NEISSERIA-GONORRHOEAE (PPNG) IN HONOLULU, HAWAII - 1982-1991 [J].
SARAFIAN, SK ;
RICE, RJ ;
OHYE, RG ;
HIGA, H ;
KNAPP, JS .
SEXUALLY TRANSMITTED DISEASES, 1994, 21 (06) :332-337
[9]  
WORKMAN RC, 1970, J INFECT DIS, V121, P434
[10]  
YEUNG KH, 1993, J CLIN MICROBIOL, V31, P3056