Cognitive Function in Kidney Transplantation

被引：22

作者：

Jurgensen, Andrew ^{[1
,2
]}

Qannus, Abd Assalam ^{[1
,2
]}

Gupta, Aditi ^{[1
,2
,3
]}

机构：

[1] Univ Kansas, Kidney Inst, Div Nephrol, Med Ctr, Kansas City, KS 66045 USA

[2] Univ Kansas, Ctr Transplantat, Med Ctr, Kansas City, KS 66045 USA

[3] Univ Kansas, Alzheimers Dis Ctr, Med Ctr, Kansas City, KS 66045 USA

来源：

CURRENT TRANSPLANTATION REPORTS | 2020年 / 7卷 / 03期

关键词：

Cognition; Kidney transplant; ESRD; MINI-MENTAL-STATE; HEMODIALYSIS-PATIENTS; RENAL-TRANSPLANT; PERITONEAL-DIALYSIS; ALZHEIMERS-DISEASE; MILD DEMENTIA; IMPAIRMENT; BRAIN; UREMIA; RISK;

D O I：

10.1007/s40472-020-00284-0

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Purpose of Review Cognitive impairment is common in kidney transplant recipients and affects quality of life, graft survival, morbidity, and mortality. In this review article we discuss the epidemiology, diagnosis, pathophysiology, and future directions for cognitive impairment in kidney transplantation. We describe the potential role of pre-transplant cognition, immunosuppression, and peri-transplant factors in post-transplant cognitive impairment. Recent Findings A majority of patients with kidney transplant have cognitive impairment. Cognitive impairment affects both pre-transplant evaluation and post-transplant outcomes. Failure to identify patients with cognitive impairment can withhold appropriate care and timely intervention. Cognitive impairment is common in kidney transplant and affects outcomes. Studies addressing modifiable risk factors and possible interventions to slow cognitive decline in patients with kidney disease are needed.

引用

页码：145 / 153

页数：9

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