Copper-catalyzed one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents toward 3-methyl isocoumarin synthesis

被引：9
作者：
Chen, Xuwen [1 ]
Liu, Yunyun [1 ]
机构：
[1] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China
来源：
RSC ADVANCES | 2017年 / 7卷 / 60期
基金：
中国国家自然科学基金;
关键词：
C-H ACTIVATION; ENANTIOSELECTIVE SYNTHESIS; DOMINO REACTIONS; COUPLING REACTIONS; CASCADE REACTIONS; FACILE SYNTHESIS; TANDEM REACTIONS; ALPHA-PYRONES; BENZOIC-ACIDS; REGIOSELECTIVE SYNTHESIS;
D O I：
10.1039/c7ra06707k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The one-pot reactions of acetyl chloride, o-halobenzoic acids and Wittig reagents providing 3-methyl isocoumarins have been furnished via tandem Wittig reaction, oxa-Michael addition and C-C cross coupling. Three new chemical bonds including one C-O, one C=C and one C-C bond are generated via the catalysis of a simple copper salt for the heterocycle construction.
引用
收藏
页码：37839 / 37843
页数：5
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