The Role of Inhaled Anesthetics in Tumorigenesis and Tumor Immunity

被引：19
作者：
Xu, Yichi [1 ]
Jiang, Wenxiao [1 ]
Xie, Shangdan [1 ]
Xue, Fang [1 ]
Zhu, Xueqiong [1 ]
机构：
[1] Wenzhou Med Univ, Affiliated Hosp 2, Dept Obstet & Gynecol, 109 Xueyuan Xi Rd, Wenzhou 325027, Zhejiang, Peoples R China
来源：
CANCER MANAGEMENT AND RESEARCH | 2020年 / 12卷
基金：
新加坡国家研究基金会;
关键词：
inhaled anesthetics; cancer; tumorigenesis; surgery; immune; TOTAL INTRAVENOUS ANESTHESIA; SQUAMOUS-CELL CARCINOMA; LUNG-CANCER CELLS; SEVOFLURANE PROMOTES; ANTITUMOR-ACTIVITY; STEM-CELLS; IN-VITRO; ISOFLURANE; PROPOFOL; SURGERY;
D O I：
10.2147/CMAR.S244280
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
dInhaled anesthetics are widely used for induction and maintenance of anesthesia during surgery, including isoflurane, sevoflurane, desflurane, haloflurane, nitrous oxide (N2O), enflurane and xenon. Nowadays, it is controversial whether inhaled anesthetics may influence the tumor progression, which urges us to describe the roles of different inhaled anesthetics in human cancers. In the review, the relationships among the diverse inhaled anesthetics and patient outcomes, immune response and cancer cell biology were discussed. Moreover, the mechanisms of various inhaled anesthetics in the promotion or inhibition of carcinogenesis were also reviewed. In summary, we concluded that several inhaled anesthetics have different immune functions, clinical outcomes and cancer cell biology, which could contribute to opening new avenues for selecting suitable inhaled anesthetics in cancer surgery.
引用
收藏
页码：1601 / 1609
页数：9
相关论文
共 61 条
[1]   SURVIVAL RATES OF BREAST-CARCINOMA PATIENTS AFTER SURGERY AND ANESTHETIC [J].
ALSABTI, E .
JOURNAL OF SURGICAL ONCOLOGY, 1979, 11 (03) :261-267
[2]  
[Anonymous], 2019, J AUST CERAM SOC
[3]   Xenon decreases cell migration and secretion of a pro-angiogenesis factor in breast adenocarcinoma cells: comparison with sevoflurane [J].
Ash, S. A. ;
Valchev, G. I. ;
Looney, M. ;
Mhathuna, A. Ni ;
Crowley, P. D. ;
Gallagher, H. C. ;
Buggy, D. J. .
BRITISH JOURNAL OF ANAESTHESIA, 2014, 113 :14-21
[4]  
Azuma K, 1993, J Anesth, V7, P442, DOI 10.1007/s0054030070442
[5]   Isoflurane, a Commonly Used Volatile Anesthetic, Enhances Renal Cancer Growth and Malignant Potential via the Hypoxia-inducible Factor Cellular Signaling Pathway In Vitro [J].
Benzonana, Laura L. ;
Perry, Nicholas J. S. ;
Watts, Helena R. ;
Yang, Bob ;
Perry, Iain A. ;
Coombes, Charles ;
Takata, Masao ;
Ma, Daqing .
ANESTHESIOLOGY, 2013, 119 (03) :593-605
[6]  
Bray F, 2018, CA-CANCER J CLIN, V68, P394, DOI [10.3322/caac.21492, 10.3322/caac.21609]
[7]   Effect of anaesthetic technique on the natural killer cell anti-tumour activity of serum from women undergoing breast cancer surgery: a pilot study [J].
Buckley, A. ;
McQuaid, S. ;
Johnson, P. ;
Buggy, D. J. .
BRITISH JOURNAL OF ANAESTHESIA, 2014, 113 :56-62
[8]   The use of isoflurane and desflurane as inhalational agents for glioblastoma surgery. A survival analysis [J].
Cata, J. P. ;
Hagan, K. B. ;
Bhavsar, S. D. O. ;
Arunkumar, R. ;
Grasu, R. ;
Dang, A. ;
Carlson, R. ;
Arnold, B. ;
Potylchansky, Y. ;
Lipski, I. ;
McHugh, T. ;
Jimenez, F. ;
Nguyen, A. T. ;
Feng, L. ;
Rahlfs, T. F. .
JOURNAL OF CLINICAL NEUROSCIENCE, 2017, 35 :82-87
[9]   The Effects of Perioperative Anesthesia and Analgesia on Immune Function in Patients Undergoing Breast Cancer Resection: A Prospective Randomized Study [J].
Cho, Jin Sun ;
Lee, Mi-Hyang ;
Kim, Seung Il ;
Park, Seho ;
Park, Hyung Seok ;
Oh, Ein ;
Lee, Jong Ho ;
Koo, Bon-Nyeo .
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2017, 14 (10) :970-976
[10]   Differential effects of sevoflurane on the metastatic potential and chemosensitivity of non-small-cell lung adenocarcinoma and renal cell carcinoma in vitro [J].
Ciechanowicz, S. ;
Zhao, H. ;
Chen, Q. ;
Cui, J. ;
Mi, E. ;
Mi, E. ;
Lian, Q. ;
Ma, D. .
BRITISH JOURNAL OF ANAESTHESIA, 2018, 120 (02) :368-375
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