Relationship between follicle number and (multiple) live birth rate after controlled ovarian hyperstimulation and intrauterine insemination

被引：19

作者：

Ghesquiere, Sophie L. ^{[1
]}

Castelain, Els G. ^{[1
]}

Spiessens, Carl ^{[1
]}

Meuleman, Christel L. ^{[1
]}

D'Hooghe, Thomas M. ^{[1
]}

机构：

[1] Leuven Univ, Fertil Ctr, Dept Obstet & Gynecol, Louvain, Belgium

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2007年 / 197卷 / 06期

关键词：

follicle number; intrauterine insemination; (multiple) live birth; (multiple) pregnancy;

D O I：

10.1016/j.ajog.2007.05.016

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVES: The goal of this study was to determine the relationship between the number of mature ovarian follicles and the ( multiple) live birth rate after controlled ovarian hyperstimulation and intrauterine insemination. STUDY DESIGN: A total of 2463 intrauterine insemination cycles performed during a natural cycle ( n = 118), or after controlled ovarian hyperstimulation with either clomiphene citrate ( n = 663) or with gonadotrophins ( n = 1682) were reviewed to assess the impact of the type of stimulation and the number of follicles 14 mm or larger on the ( multiple) live birth rate per cycle. RESULTS: The live birth rate after intrauterine insemination was significantly higher (P=.02) after stimulation with gonadotrophins (13%) than after clomiphene cirate (8%) if only 1 follicle 14 mm or larger was present. If 2 or more follicles were present, there was no statistically significant difference between both stimulation methods. CONCLUSION: Treatment of intrauterine insemination with gonadotrophin is effective with an acceptable ( multiple) live birth rate when 1 or 2 follicles 14 mm or larger are present.

引用

页码：589.e1 / 589.e5

页数：5

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